The herpes simplex virus (HSV) may be not only a nosological disease but also a secondary infection
which may affect the severity of the course of other dermatoses.
On time diagnostic's and proper therapy of the psoriasis progression help related specialists prevent
occurrence of such diseases. Therefore, the goal of our research is to provide comprehensive
examination of the persons suffering from psoriasis, especially those with the severe or atypical course of
the disease, in order to detect herpetic infection and improve further treatment of these patients. 

Psoriasis is one of the most common chronic, non-communicable, immune-mediated skin diseases,
affecting over 125 million people worldwide. The means and dosage forms of topical therapy depend
usually on the clinical course pathological process. In recent years, both in the world and in Ukraine,
narrowband UVB phototherapy of psoriasis, because of its efficiency, safety and availability has become a
technique of choice in the treatment of psoriasis patients with different clinical course. NB UVB therapy
method is self-contained and can be used as monotherapy, but combination of emollient, in our view,
adds treat certain advantages. The aim of our study was to examine and evaluate the effectiveness of this
method phototherapy combination of emollient in the treatment of psoriasis. 

The global trend in COVID-19 is that the virus permanently turns into a seasonal disease, such as the flu.
Every year, people will face the problem of the coronavirus, which will continue to mutate. The known
and studied nature of COVID-19 mutations currently does not indicate that the virus has become more
aggressive for the human body. More and more often, COVID-19 proceeds as an acute respiratory viral
infection and evades an immune response. 

Acne is a multifactorial chronic inflammatory disease with primary damage to the pilosebaceous unit and
the polymorphic clinical manifestations associated with overproduction of sebaceous glands,
pathological desquamation of the sebaceous epithelium of the sebum follicles, activation of saprophytic,
conditionally pathogenic microorganisms, and psychoemotional disorders. This is undoubtedly one of
the most common dermatoses in clinical practice, accounting for 20-25% of dermatology consultations.
Today, especially in wartime, acne vulgaris remains a socially important problem in approximately half of
patients with psychoemotional disorders, mainly of a depressive and anxiety associated nature with a
sharp decrease in the quality of life of patients. 

Introduction In recent years, dermatologists and cosmetologists have increasingly paid attention to the
problem of the relationship between skin diseases and the organs of the gastrointestinal tract (GI).
Numerous clinical and microbiological studies confirm the connection between gastrointestinal
pathology and intestinal dysbacteriosis with inflammatory skin diseases. The purpose of our study was to
investigate the influence of the intestinal microbiocenosis on the severity of acne (AC)