Background: The diagnosis of adnexal torsion is challenging due to the absence of specific symptoms that can determine the postponing of surgery, and as the consequence, the development of necrotic changes of adnexa. Nowadays, the surgical treatment of patients with this pathology shifting to the ovary-sparing surgery (detorsion) despite to the presence of necrotic changes during surgery. By that, the question of the choice of the method of treatment in case of adnexal torsion still under debate between pediatric surgeons and gynecologists

Aim of the study was to summarize the own experience in treatment of patients with adnexal torsion

Methods: This study was based on the results of retrospective and prospective analysis of treatment of 73 patients with adnexal torsion, who were operated at Lviv Regional Children’s Clinical Hospital «OHMATDYT» during 2010-2022 years. Diagnosis was established on results of clinical investigation and ultrasonography (US). It was performed 74 surgical procedures (one patient was operated twice), among them 57 (77%) by laparoscopic and 17 (23%) by open approach (laparotomy). It was 49 (66,2%) ovary-sparing surgeries (detorsion with or without cystectomy) and 25 (33,8%) – adnexectomy.

Results of the study were evaluated by the statistical program StatPlus: mac, AnalystSoft Inc. (version v8). Results: The average age of patients was 11,5±0,5 years. Abdominal pain (in 100%) and vomiting (in 49,3%) were the main clinical appearances. Unilateral ovarian enlargement and peripherally displaced follicles were the most frequent US findings. The absence of the blood supply was revealed in 39,5% and the whirlpool sign in 11,6% of patients. Among all patients, simple torsion confirmed in 24,3%, while the torsion caused by cyst or dermoid tumor, revealed in 75,7% of patients. Detorsion was performed only in 24,3% of patients and in 42,5% of patients it was supplemented by cystectomy. Adnexectomy was performed in 32,2% of patients.

Conclusions. The diagnosis of adnexal torsion should be considered in all females with acute abdominal pain syndrome. Ultrasonography with or without Doppler is the first-line imaging modality. Detorsion was performed regardless of the degree of torsion, and indications for adnexectomy were the presence of a dermoid cyst and clear signs of ovarian necrosis. Laparoscopic detorsion, simple or with cystectomy, is the method of choice for treatment of patients with adnexal torsion. (TCM-GMJ June 2024; 9 (1):P23-P27)

Мета дослідження – визначити соматометричні особливості чоловіків 26–31 року.  Аналіз даних показав, що за більшістю масо-зростових показників фізичного розвитку (маса тіла, ІМТ, індекс Рорера) між чоловіками 26–28 років та 29–31 року існували значущі відмінності. Чоловіки 29–31 року мали більші середні значення маси тіла, ІМТ та індексу Рорера порівняно з чоловіками 26–28 років, що свідчило про тенденцію до збільшення маси тіла та зростання відповідних індексів з віком. 

Introduction. The stroke volume (SV) is an important indicator of the cardiovascular system activity, namely the maintenance of systemic hemodynamics. Its changes in the training process can indicate the formation of the level of training, or the processes of recovery of the body after loads. The purpose of this work was to determine the changes in the SV when performing tests with controlled breathing, as well as to investigate the correlations with the breathing pattern. 

Introduction and aim. The aim of this work is to study the parameters of the nitric oxide (NO) system in the blood of guinea pigs under the conditions of the experimental periodontitis (EP) and immobilization stress (IS) formation and to evaluate the effectiveness of thiocetam use.
Material and methods. Experimental studies were performed on 50 guinea pigs (males, body weight 0.18–0.21 kg) which were divided into five groups (10 in each): the first group were intact animals as control; the second experimental group were animals with experimental periodontitis under conditions of immobilization stress (3rd day), the third group included guinea pigs with EP and IS on the 5th day of the combined model process, group IV – animals with EP and IS 15th day (without administration of thiocetam) and group V – animals on the 15th day of experiment with EP and IS after use of thiocetam.
Results. As a result of this research, changes in the activity of the NO system in the blood were observed, namely an increase in the level of stable metabolites and an increase in the activity of total NO-synthase, which is accompanied by a compensatory inhibition of the L-arginine activity, and these indicators were most pronounced in the late stages of EP and IS formation.
Conclusion. The use of thiocetam showed a corrective effect on the changed variables of NO metabolism in the peripheral blood of guinea pigs under the conditions of the EP and IS development
 

To determine changes in the parameters of cardiorespiratory relationships during the maneuver with a change in breathing rate after a 4-month cycle of training aimed at the development of strength endurance.  Endurance training for 4 months led to an economization of the cardiovascular and respiratory systems function and a decrease in the response to sympathoadrenal activation and hyperventilation.