Metabolic physiology plays a key role in maintaining our health and resilience. Metabolic disorders can lead to serious illnesses, including obesity. The pathogenesis of the new long COVID syndrome in individuals with long-term recovery after SARS-Co-2 infection is still incomplete. Thus there is growing attention in the study of adipose tissue activities, especially brown adipose tissue (BAT) and associated resilience which plays a crucial role in diferent types of obesity as potential targets for pharmacologic and nutritional interventions in the context of obesity and long COVID. The number of studies examining mechanisms underlying BAT has grown rapidly in the last 10 years despite of role of BAT in individuals with COVID-19 and long COVID is modest. Therefore, this review aims to sum up data examining BAT activities, its resilience in health, obesity, and the possible link to long COVID. The search was conducted on studies published in English mostly between 2004 and 2022 in adult humans and animal models. Database searches were conducted using PubMed, Scopus, and Google Scholar for key terms including adipose tissue, BAT, adipokines, obesity, VPF/VEGF, and pathogenesis. From the initial search through the database were identifed relevant articles that met inclusion and exclusion criteria and our data regarding adipose tissues were presented in this review. It will discuss adiposity tissue activities. Current literature suggests that there are BAT integral efects to whitening and browning fat phenomena which refect the homeostatic metabolic adaptive ability for environmental demand or survival/adaptive mechanisms. We also review neural and vascular impacts in BAT that play a role in resilience and obesity. Finally, we discuss the role of BAT in the context of long COVID in basic research and clinical research.

On October 14, 2022, the 6ᵗʰ International Symposium “SMART LION” (Science Medicine Arts Research Translational Lviv International Opportunity Network) was held in Lviv with the support from Danylo Halytsky Lviv National Medical University, the Medical Commission of  the Shevchenko Scientific Society, Lviv City Council and Lviv Conference Bureau. It was no coincidence that the time of the conference coincided with the Day of Defenders of Ukraine,  which include military medical professionals and scientists who equip them with knowledge  and skills enabling them to save lives on the battlefield.  The purpose of the symposium was to analyze the new experience of medical professionals  and volunteers of Ukraine and its allies, which they acquired during russia's war against  Ukraine, develop new methods in medical education, and establish close cooperation between military medical professionals, volunteers, and scientists.  The scientific event was held online via ZOOM. It was also streamed on the Facebook page of the journal “Proceedings of the Shevchenko Scientific Society. Medical Sciences”. The event  featured more than 20 speeches by international and domestic scientists and highly qualified specialists. Subsequently, they will serve as a scientific and practical foundation for the development of both military and general medicine. Discussions during the conference clearly showed the need for systemic changes in medical education, supplementing educational programs taking into account the vast experience of military medical professionals, and improving teaching methods. At the end of the symposium, organizers expressed confidence that most of the deliverables  and ideas highlighted during the conference will be successfully implemented. We sincerely thank all defenders and allies of Ukraine, volunteers and medical professionals who save people's lives, sometimes pulling them out of the death grip. With hope for and belief in a bright future, with faith in an upcoming victory and plans to meet again live in Lviv at SMART LION 2023

Tubal factor infertility is one of the most pressing problems of our time, as this condition makes it impossible for a mature organism to produce offspring. The issue of restoring and preserving reproductive health is one of the priority problems of modern gynaecology and reproductive medicine. Therefore, in terms of reproductive health care as a fertility factor, the main focus is on those strategies that can help reduce reproductive losses. In recent years, Ukraine has been experiencing an insufficient level of reproductive health due to the negative impact of socio-economic instability in the country, martial law, falling living standards, and natural conditions. In addition, the ongoing opioid epidemic is a major burden on society and has a detrimental impact on future generations. Many literary sources contain information about the significant adverse effects of opioids on women's reproduction. The fallopian tube is crucial in the mother's interaction with gametes and embryos. For both human and female laboratory white rats, it takes almost four days for the oocytes to pass through the fallopian tube to the uterus. Defects associated with these processes can lead to infertility, which has motivated a wide range of research into the causes and treatments of pathological conditions of the fallopian tube.The article highlights the links of tubal-peritoneal infertility, namely the effect of the narcotic analgesic Nalbufin on the morphometric parameters of the components of the mucous membrane of the ampulla of the fallopian tube: the thickness of the mucous membrane, the thickness of the mucous membrane lamina propria, the width and length of the fold of the mucous membrane of the ampulla of the fallopian tube of the female white rat.