Abstract. Background. Obesity is one of the most acute health care problems. Numerous methods of combating excess body weight have been developed, but the existing strategies do not lead to permanent and proportional weight loss, some of them have a number of contraindications and side effects, so new methods of body weight correction are constantly being sought. A short-term low-carbohydrate and low-fat diet with additional use of amino acids is promising. The purpose of the study was to evaluate the efficacy of a 21-day low-carbohydrate and low- fat diet with the additional use of an amino acid complex for weight loss.
Materials and methods. Thirty-seven women with a diagnosis of obesity were involved. They were randomly divided into two groups — experimental (19 women) and control (18 women), with the same age, body weight and results of bioimpedance analysis. The patients of the control group were put on a hypocaloric Mediterranean diet, and the patients of the experimental group — on a low-carbohydrate, low-fat diet with the additional use of an amino acid complex. Duration of observa- tion was 21 days. Before and after completion of observation, all patients underwent anthropometric measurements.
Results. After 21 days, the experimental group had a greater decrease in body weight compared to the control group (6.7 ± 0.4 % vs. 3.8 ± 0.7 %, p < 0.05), in body volumes (chest volume: 4.3 ± 0.4 % vs. 1.9 ± 0.4 %, waist volume: 5.2 ± 0.2 % vs. 2.2 ± 0.4 %, hip volume: 5.1 ± 0.3 % vs. 2.3 ± 0.5 %, all p < 0.05). In this group, there was also a greater decrease in adipose tissue (13.6 ± 0.8 % vs. 7.0 ± 2.0 %, p < 0.05), and in the degree of visceral obesity (2.0 ± 0.2 units vs. 0.9 ± 0.3 units, p < 0.05); the amount of muscle tissue, on the contrary, increased (–2.3 ± 0.6 % vs. 2.6 ± 0.7 %, p < 0.05).
Conclusions. There was a significantly greater decrease in body weight, in main body volumes, a greater reduction in adipose tissue and the degree of visceral obesity in patients who were on a low-carbohydrate and low-fat diet with additional use of amino acids compared to patients who ate according to the conventional method.
Keywords: obesity; normalization of body weight; ketogenic diet; bioimpedance analysis

УДК 616.1/.4-036.1-06-07-08(063)

Гострий розлад мозкового кровообігу (ГРМК) є другою за частотою причиною смерті й головним чинником інвалідності в усьому світі. Одним із провідних чинників обмеження життєдіяльності людей є порушення рухових функцій верхньої кінцівки внаслідок перенесеного ГРМК, що спостерігається майже у 75% пацієнтів. Внаслідок порушення моторної функції верхньої кінцівки, виникає дефіцит діяльності та участі, що призводить до різкого погіршення якості життя пацієнта та його родини. 

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