UDC 618.03-06:616.441-002-073.7:612.882.3
Thyroid disease is the second most common endocrine disorder after diabetes inpregnancy.Thyroidhormonesarecrucialforthegrowthandmaturationofmanytargettissues,especiallythebrain and skeleton. During critical periods in the first trimester of pregnancy, maternal thyroxine is essential forfetal development as it supplies thyroid hormone-dependent tissues. The purpose of the study was to researchthe features of the bioelectrical activity of the brain in pregnant women with thyroid pathology and determine thefrequency of such changes. Materials and methods.The state of bioelectrical activity of the brain was evaluatedby electroencephalography in 160 pregnant women with thyroid pathology. The biopotentials of the brain in thesubjects were studied with software and hardware complex DX-NT32 (DX Complexes software, Kharkiv, Ukraine)and computer processing of electroencephalography data. Electrodes in the amount of 16 pieces were appliedaccording to the international scheme 10/20 in the bipolar interpretation. Results. Specific changes in electro-encephalograms characteristic of each type of thyroid pathology and dependent on its severity were revealed inpregnant women. Acquired disorders adversely affect the course of pregnancy and childbirth in women with thyroidpathology. Increased anxiety with depressive tendencies, reduced general activity, a feeling of depression, anxiety,and low mood were detected in women with thyroid disorders. The identified criteria make it possible to attributethese changes to the manifestations of a pathological neurotic state in conditions of maladaptation, which wasconfirmed by electroencephalography data. Conclusions. The detected disorders of spontaneous and evokedbrain activity indicate the existence of a cerebral basis of psychological stress, which has a qualitative effect onelectroencephalography. Acquired disorders negatively affect the course of pregnancy, childbirth, perinatal out-comes, and future development of the child.Keywords:pregnant women; thyroid gland; diffuse non-toxic goiter; diffuse toxic goiter; electroencephalography