Abstract. The research substantiates Japanese experience of media literacy and oral communication skills development by digital storytelling (DST); reveals theoretical background and current practical application of DST in higher education of Japan. DST has significant advantages as an individual- and situation-oriented tool of oral communication as well as the instrument of psychological and learning influence on society. It is continuously implemented into Japanese educational and social practice. Famous universities of Japan initiate and realize scientific and academic projects, extending communication connections of Japanese population, improving their skills of critical thinking and argumentation, developing desires and abilities to communicate freely, fluently, confidently and persuasively. At present DST shows a positive growing tendency as a teaching and learning tool in higher education of both Japan and Ukraine. This is primarily linked with the global processes of social digitalization, computerization of education and urgent transferring to distance learning due to the COVID-19 pandemic. Evidence-based studies prove the efficacy of DST as the learning and evaluation instrument of oral communication skills, i. e. in English. Moreover, the technology can be applied in different specialties, i. e. medical one. The healthcare branch was drastically influenced by quarantine restrictions, having resulted in fundamental transformations of teaching and learning approaches, implementation of e-learning and telemedicine. DST has a confirmed positive influence on public health and medical knowledge development. In higher medical education it can be used as a new type of virtual patients. DST can improve physician-patient communication skills, professional qualities, tolerance and empathy. Our research confirms the potential of DST as a powerful developmental tool of media literacy and oral communication skills, and proves the requirement for the implementation of Japanese experience into higher education of Ukraine.

Introduction: Enterobiasis is the most common parasitosis in the world. The literature rarely presents publications on the detection of pinworm eggs in the urine, especially in chronic inflammatory processes of the urinary system.

Materials & Methods: We analyzed publications over the past 10 years of detection of this pathology.

Results&Discussion: The presented results show the feasibility of detecting enterobiosis by urinalysis, which can significantly improve the diagnosis and treatment of enterobiosis.

Background: We examined the human toll and subsequent humanitarian crisis resulting from the Russian invasion of Ukraine, which began on 24 February 2022.

Method: We extracted and analysed data resulting from Russian military attacks on Ukrainians between 24 February and 4 August 2022. The data tracked direct deaths and injuries, damage to healthcare infrastructure and the impact on health, the destruction of residences, infrastructure, communication systems, and utility services - all of which disrupted the lives of Ukrainians.

Results: As of 4 August 2022, 5552 civilians were killed outright and 8513 injured in Ukraine as a result of Russian attacks. Local officials estimate as many as 24 328 people were also killed in mass atrocities, with Mariupol being the largest (n=22 000) such example. Aside from wide swaths of homes, schools, roads, and bridges destroyed, hospitals and health facilities from 21 cities across Ukraine came under attack. The disruption to water, gas, electricity, and internet services also extended to affect supplies of medications and other supplies owing to destroyed facilities or production that ceased due to the war. The data also show that Ukraine saw an increase in cases of HIV/AIDS, tuberculosis, and Coronavirus (COVID-19).

Conclusions: The 2022 Russia-Ukraine War not only resulted in deaths and injuries but also impacted the lives and safety of Ukrainians through destruction of healthcare facilities and disrupted delivery of healthcare and supplies. The war is an ongoing humanitarian crisis given the continuing destruction of infrastructure and services that directly impact the well-being of human lives. The devastation, trauma and human cost of war will impact generations of Ukrainians to come.

The aim of the study is to identify the expectations of physicians (provisors)-interns for postgraduate education and assess their satisfaction with the course of primary specialization (internship). The sociological crossectional study was performed in 2021 by surveying interns of Danylo Halytsky Lviv National Medical University majoring in the following medical specialties: “Medicine” and “Pediatrics”, “Dentistry”, “Pharmacy”. The survey took place in two groups: applicants at the beginning of the internship (n=655) and after completion of the internship (n=623). Statistical methods (which are represented with confidence intervals calculated by the Fisher’s angular transformation method), structural-logical analysis and a systematic approach were used. The study revealed that the most effective form of training in the full-time internship cycle are practical classes and conferences for physicians(provisors)-interns; the least effective form is independent work. The main factors that prevented the interns from mastering the professional knowledge, skills and abilities of the internship cycle are limited opportunities for independent supervision of patients, material and technical equipment of the clinical base of the department and the interns’ own inertia. Certain shortcomings in the organization of the practical part of the internship on the basis of the hospital / pharmacy were established, namely: lack of supervision of patients, lack of practical activities, unsatisfactory material and technical equipment and disinterest of the staff in the training of interns. According to interns, the ideal model of internship should be available, that would provide the optimal amount of theoretical knowledge and relevant practical skills and would be as relevant to the future work of the physician as possible. Applicants emphasize the qualitative component of obtaining postgraduate medical education: the use of new treatment protocols, training in hospital of the third level of medical care, the possibility of doing internships abroad. Such sociological surveys among physians (provisors)-interns on their satisfaction and compliance with expectations are an important component of the development of an optimized Model of postgraduate education of doctors / provisors in Ukraine, which will improve the quality of primary specialization (internship), the ultimate goal of which is health preservation and improvement of the life expectancy of Ukrainian citizens.

The aim. The purpose of this review is to summarize data on the synthesis and structural modification of heterocyclic systems with triazole and thiadiazole fragments in molecules as promising objects in bioorganic and medicinal chemistry.

Materials and methods. The research based on bibliosemantic and analytical methods using bibliographic and abstract databases, as well as databases of chemical compounds.

Results. Modern medicinal chemistry faces many challenges, one of which is the determination of the activity and specificity of therapeutic agents. Recent scientific data showed that triazoles and/or thiadiazoles have broad spectrum of biological activities, in particular antimicrobial, antifungal, antiviral, anticancer and anticonvulsant. Synthetic research allows to propose a whole number of new molecular design directions of biological active triazole and/or thiadiazole derivatives, as well as to obtain directed library that include hundreds of new compounds. This review is an effort to summarize data of its analgesic and anti-inflammatory activity over the last decade. We summarized and analyzed the series of triazole and/or thiadiazole derivatives and provided data of their structure-activity relationship. For optimization and rational design of highly active molecules with optimal «drug-like» characteristics and discovering of possible mechanism of action SAR, QSAR analysis and molecular docking were summarized.

Conclusions. It has been shown that heterocyclic systems containing fragments of triazole and / or thiadiazole are a significant source of promising analgesic and/or anti-inflammatory agents. It has been established that the mentioned heterocyclic derivatives have a high selectivity of action, low toxicity and an effect commensurate with standard drugs