Laser therapy is a complex of hardware procedures that involve exposure of the skin to light energy and allows getting rid of a number of skin imperfections. The results of the therapy using the Nordlys device, the principle of operation of which is based on the theory of selective photothermolysis, were analyzed and presented. We observed 118 patients (42 men and 76 women aged 18 to 65 years) with different dermatological problems. The Dermatology Life Quality Index (DLQI) was used to determine the effectiveness of the treatment.

Acne is currently referred to a group of dermatoses that cause somatopsychic resonance due to existing or anticipated aesthetic discomfort. A significant impact of the disease on the quality of life was observed in all examined women with acne, the greatest impact being on daily activities and private life, especially in patients with the disease duration of 1 to 5 years. An increase in the level of anxiety, especially the trait one, was also observed in the group of women with duration of the disease of 1 to 5 years. This substantiates the necessity to find new comprehensive methods of treatment for patients with acne, taking into account the impact of the disease on the anxiety and quality of life of patients.

Nowadays dermatologist’s arsenal contains numerous pharmacological agents with high efficiency, but achieving the desired results in acne therapy is still not the easiest problem. The undisputed leader in the treatment of acne, taking into account the frequency of prescriptions, effectiveness, active substances as mono- and combined forms, lack of systemic influence, are topical medicines. As a result, groups of the most effective medical agents for acne therapy, features of their use in different forms and degrees of severity, possible side effects and factors that can provoke them, ways to minimize their occurrence without reducing effectiveness were identified.

Today, the use of platelet-rich plasma is increasing in clinical practice in various fields of medicine. The plasma therapy is used by dermatologists, dentists, gynecologists, traumatologists and many other specialists in daily practice. Platelet-rich plasma is actively used in dermatology after its clinical effectiveness has been established. The plasma therapy method alone, as well as in combination with other methods of treatment, has shown advantages in certain skin diseases: androgenetic alopecia, alopecia areata, chronic vitiligo, melasma, inflammatory nail disorders, psoriasis, acne, post-acne and seborrheic dermatitis. Platelet-rich plasma can suppress cytokine release and limit inflammation by interacting with macrophages, improving tissue healing and regeneration, promoting the formation of new capillaries and accelerating epithelialization. Plasma platelets also play an important role in the host’s defense mechanism at the wound site by producing signaling proteins that attract macrophages. Blood plasma also has antimicrobial activity against Escherichia coli, Staphilococcus aureus, Candida albicans and Cryptococcus neoformans.