Під нашим спостереженням перебувало 67 хворих на хронічний генералізований пародонтит 1 і 2 ступеня важкості у фазі загострення без істотних супутніх захворювань. При встановленні клінічного діагнозу використовували загальноприйняті методи. Пацієнтів основної групи (36 осіб) лікували за допомогою запропонованого засобу, в контрольній групі (31 особа) – застосовували традиційну терапію. Для оцінки ефективності лікування визначали пародонтальний індекс (Russel, 1967), вимірювали глибину пародонтальних кишень, з метою об’єктивізації результатів впродовж усього спостереження контролювали гігієнічний стан ротової порожнини. Отримані нами клінічні дані оцінювали безпосередньо після лікування, а також через один і три місяці після нього.

Результати. Спостереження за пацієнтами основної групи засвідчило, що застосоване лікування спричинило швидку ліквідацію симптомів запалення вже після 1-2 сеансів терапії. Бажаний терапевтичний ефект від проведеного лікування в основній групі зафіксований в 78% випадків, у контрольній – у 51%.

Висновки. Запропоновані нами лікарські форми – гель та плівка на основі амізону є ефективними засобами для лікування пародонтитів, вони зручні у використанні, не викликають побічних ефектів і можуть бути рекомендовані для широкого клінічного застосування. Ключові слова: лікування пародонтиту, гель, плівка, амізон. 

The study aims to review the involvement of different dietary habits in Laotian, Cambodian, and Vietnamese populations in reducing COVID19 impact.
Materials and Methods. The methods of collection, systematization, analysis and generalization of information data have been used. The analysis of literature in scientific databases and analytical platforms by the listed keywords has been performed; all relevant references in the found sources have also been reviewed.
Results and Discussion. Coronavirus disease (COVID-19) outbreak is an ongoing pandemic caused by a highly pathogenic human coronavirus known as SARS-CoV2. Current epidemiology reported that more than 500 million cases of COVID-19 occurred in more than 180 countries worldwide. When the upper respiratory tract gets infected
by low pathogenetic HCoVs, it typically triggers a mild respiratory disease. In contrast, when the lower airways get infected by highly pathogenic HCoVs, such as SARSCoV2, acute respiratory distress syndrome (ARDS) may occur and even fatal pneumonia. Such a situation causes the need for an urgent search of effective treatment measures. A very low incidence of SARS-CoV-2 in Laos and Cambodia, as well as low mortality rate due to COVID-19 in Vietnam and Laos, are extremely interesting, especially because of their early exposure to the virus, continuing ties to China, relative poverty, and high population density. The use of several spices and aromatic herbs as natural treatments for several illnesses, including viral infections, has been reported since a long time ago. The research reviewed three integral elements of Laotian, Cambodian, and Vietnamese diets, such as special culinary spices and herbs, coconut oil, and palm oil-rich for saturated fatty acids as well as fermented shrimp paste. Environmental and population genetic
causes may be forwarded but moreover local dietary habits may have even a role in this evidence. Therefore, all these items highlight the possibility of a significant contribution of local cuisine and diet into the impact on  appropriate anti-inflammatory and immune-resistant mechanisms of the human population.
Conclusions. The review on Vietnam, Cambodia, and Laos inhabitants' diet helped to suggest the dietary factors having the contributing potential of reducing the severity of SARS-CoV-2 symptoms

Keywords: COVID-19, spices and herbs, Indo-Chinese cousin, ginger, black pepper, coconut oil, fermented shrimp paste

 УДК 616.314.085.454.1.546.28

При патології пародонта часто розвивається хвороблива зміна макрорельєфу ясен, яка супроводжується гіпертрофією чи рецесією ясен з оголенням коренів зубів та розвитком патології цементу. Макрорельєф контуру ясен ми характеризували терміном гінгівогліфіка. Нами досліджено, що особливості контуру та макрорельєфу ясен можуть формувати аркадний, балонуючий, сплощений та змішаний типи гінгівогліфіки. При хворобах пародонта часто формується патологічний макрорельєф контуру ясен: змішаний – 8,56%, сплощений – 6,29%, балонуючий – 4,23%, посилено-аркадний – 3,28%. Знання особливостей гінгівогліфіки дозволяє краще планувати та прогнозувати лікування пацієнтів із патологією пародонта.

Ключові слова: патологія пародонта, маргінальний пародонт, гінгівогліфіка, рецесія ясен 

 . One of the problems in standardizing Bioadhesive dental film (BDF) produced by the solvent casting method, is the use of a Casting Mould with clearly set geometrical parameters of 10.0 x 60.0 mm, when using a set volume of polymer gel. Many scientific studies dealing with the preparation of polymeric medical film fail to describe the technological equipment necessary for the manufacture of BDF (bio dental films) using the solvent casting method on a flat surface.

During the scientific development of this process, three types of devices were designed, tested and patented, these being a Casting Mould, and Perforating and Cutting Devices to be applied in the production of dental BDF using the solvent casting method.

The Casting Mould is made of a neutral glass and has the dimensions of 60 x 400 mm which allows the tie production of dental films of a standardized size using the solvent casting method. The Perforating Device results in improved perforated BDF in the process of its production. Meanwhile the Cutting Device allows the uniform distribution and cutting of the polymer film into dozaged strips with accurately specified geometrical dimensions of 10.0 x 60.0 mm. 

Biometric parameters of fruits and seeds of Paulownia tomentosa collected from trees growing in soil and climatic conditions of different geographical locations of Odesa, Zakarpattia (Mukachevo) and Lviv regions of Ukraine, as well as technical and absolute germination, germination energy, mean germination time and weight of 1000 seeds, were studied. The effect of different temperatures on seed germination in soil was evaluated under two temperature regimes. The influence of the duration of pre-soaking on seed germination was also determined. Pre-soaking
of seeds in water and solutions of five different stimulants on germination in soil was also investigated. It has been found that in the conditions of Odesa region, the species formed larger fruits and the seeds were characterized by significant rate and uniformity of germination. Lowering of germination temperature caused a decrease in germination energy, laboratory and absolute seed germination, and increased the mean germination time of seeds. Pre-soaking of seeds increased significantly germination rate and its duration was associated with the parameters: germination energy, technical and absolute germination. Among the three seed collections, the highest technical germination was recorded for seeds from Lviv region. The seeds from Odesa region had the highest germination energy. The seeds were characterized by high germination rate in soil regardless of the geographical location of seed collection under the conditions of Ukraine. The highest germination in soil was found for seeds, collected in Lviv. Temperature during germination significantly affected the germination of seeds in soil. Under the temperature regime of 21 to 25 °C, soil fertility parameters were significantly higher. Pre-soaking of seeds had the highest stimulating effect on further germination of seeds in soil among the studied treatments. Pre-treatment of seeds with germination stimulants had generally a positive effect, increasing germination in soil.
Key words: biometric parameters, germination, pre-soaking, stimulators, temperature regimes, weight of 1000 seeds