УДК: 616.89-008.441.14: 616.716.8-018.46-002]-036-099

   Appropriate surgical tactics and pathogenetic therapy are of great importance for toxic osteomyelitis in drug addicts. Therefore, in our study, with long-term integrated treatment, systemic and pathogenetically conditioned drug therapy was used, and appropriate surgical treatment, aimed at removal of necrotized areas of the mandibular bone, was performed. We believe that due to the treatment, despite the total destruction of the mandible, it was possible to stop the destructive bone processes and to preserve life for such a patient and to create conditions for subsequent reconstructive operations. The treatment was aimed at reducing the disability of patients with the persistent rejection of substance abuse.