УДК 616.98:579.834.114-053.2
Abstract. Neuroborreliosis constitutes a neurological sequelae of Lyme disease, due to the pathogenic activity of the spirochetal agent, Borrelia burgdorferi. Transmission of this microorganism to human hosts occurs through the bite of an infected tick. The persistent intracellular presence of Borrelia burgdorferi gives rise to a primary cutaneous manifestation known as erythema migrans. Later, at advanced stages of the
disease, it can lead to central nervous system involve. The aim is to present a case study of a 15-year-old female patient with neuroborreliosis, a neurological complication of Lyme disease, and to discuss the possible mechanisms of this complication. Material and methods. Clnical, laboratory, instrumental examination and neurological status assessment of the patient M revealed the Facial muscles palsy on the left side of the face, with no signs of Meningitis. The hospital conducted tests for Borreliosis, a lumbar puncture, and an MRI of the brain. Results. This clinical report demonstrate the progression of neuroborreliosis, marked by encephalitis and facial nerve palsy, in a 15-year-old female patient. Unfortunately, Lyme borreliosis was detected in the late stages of the disease because the primary symptoms that occur in the early, localized stage - erythema migrans - were сomitted. Nonetheless, the identification of neuroborreliosis and the implementation of appropriate therapeutic interventions (Ceftriaxone & Doxycycline, Prednisolone, Acetazolamide prescription) facilitated the patient’s recovery. The discussion presents possible mechanisms for the development of this complication. Conclusions. With this clinical case, we aimed to demonstrate the development of neuroborreliosis with encephalitis and palsy of the facial nerve in an 15-year-old girl, the rare childhood diseases in our regions. Unfortunately, Lyme borreliosis was detected in the late stages of the disease because the primary symptoms that occur in the early, localized stage - erythema migrans - were omitted. However, the diagnosis of neuroborreliosis
and adequate treatment contributed to the patient’s recovery. The discussion presents possible mechanisms for the development of this complication.
Key words: Neuroborreliosis, Lyme diseases, Encephalitis, Facial nerve palsy, children, treatment.