Some cases of asymptomatic traumatic cyst can be sizeable; therefore, they require complete curettage and grafting with bone substitution materials. This case report presents a sizeable traumatic mandibular cyst in a young man treated by surgical exploration and flled with autologous dentin graft (ADG) prepared from extracted an impacted tooth 48 (FDI tooth-numbering system) and advanced platelet-rich fbrin (A-PRF). Initially, an A-PRF membrane was used to cover the apices of teeth 42 and 43, which were protruding into the defect to protect their periapical structures. Then, a grafting strategy was introduced to achieve two fronts of bone formation: one by stimulation of bone outgrowth from the periphery due to A-PRF cellular activity, and a second by bone deposition directly on dentin particles in the center of defect. On CBCT scans performed 7 months postoperatively, arrays of trabeculae that were extending from bone boundaries of the cyst defect were merged with more condensed bone deposited on ADG residuals in the center, thus flling the defect. It was found that autologous dentin combined with cellular A-PRF activity is a powerful tool to restore even sizable bone defects in a relatively short time frame with adequate bone remodeling. 

Introduction. To determine the primary events of gingival microvascular complex damage caused by inflammation (28 days) on an acidotic model of periodontitis in 36 white mongrel rats, and to clarify regulatory factors of the structural recovery after metabolic correction (14 days). Materials and methods. Expression and severity of gingival inflammation were visually analyzed with an ANOVA test. The gingival tissue specimens were examined (x 4000-6000) after 42 days with a transmission electron microscope JEM-100 CX II (JEOL, Japan). Results and discussion. Vacuolation of the endothelial cells' cytoplasm, thickening and loosening of the basal lamina, narrowing of the microvascular lumen, aggregation of the red blood cells and dilation of perivascular space were characteristic features of inflammatory derangement. A significantly lower severity of gingival inflammation (p < 0.05), thin condensed basal lamina …

ABSTRACT
The aim: of our work was investigation of dystrophy in periodontal tissues and an attempt to establish the correlation between dystrophy in the periodontium and presence of intestinal disbacteriosis.
Materials and methods: Clinical-radiological examination was carried out in 146 patients with generalized periodontal pathology at the age from 26 to 59 years old. Among them in 92 persons generalized periodontitis was diagnosed and in 54 – periodontosis. The rst stage of heaviness of the pathological process in the periodontium was revealed in 50 patients with generalized periodontitis and 28 persons with periodontosis. Other patients su ered from heavier forms of periodontal pathology (II and III stages), 42 persons with generalized periodontitis and 28 persons with periodontosis accordingly. Bacteriological analysis of feces for disbacteriosis was carried out in all patients.
Results: Changes in the physiological contour of the gums (that is macro relief of marginal periodontium) were found in the majority of examined patients. Because of the development of pathological gingival contour and recession of the gums, 72,5% of examined patients su ered from root denudation and di erent pathological conditions of roots cement structure – pigmentation, demineralization, wedge-shaped defects, caries. According to our clinical investigations it was found out that in majority of patients (83%) both in ammatory and dystophic changes were present, only 17% of patients had purely atrophic process in the periodontium without in ammation. In patients with GP and periodontosis, in whom dystrophic changes were accompanied by in ammation, clinical appearance was more expressed with redness, bleeding and suppuration from the pockets, thus hiding dystrophic signs.
Conclusions: According to clinical and radiological ndings numerous dystrophic changes were found in all structures of the periodontium and teeth of patients with periodontosis and generalized periodontitis. Changes intensify in disease progressing into the II-III stages. In patients with periodontosis clinical- radiological peculiarities of dystrophy were revealed in early stages of disease progression, while in generalized periodontitis dystrophic changes become apparent in late stages of disease. The presence of colon disbacteriosis was established in patients with periodontosis and generalized periodontitis. Disbacteriosis intensi es when diseases progress into II-III stages of heaviness. These data indicates to possible correlation between the development of dystrophic changes in periodontal tissues and the presence of intestinal disbacteriosis.
KEY WORDS: intestinal disbacteriosis, generalized periodontitis, periodontosis, dystrophy, gingival contour

Aim: To determine the role of damage to the ultrastructural elements of the periodontal nervous system in the pathogenesis of dystrophic periodontal disease.
Materials and Methods: The basis of the experimental part of the study was the preparation of ultrathin sections from blocks of gum tissue of white rats, which were prepared using the UMTP-3M device. The study and analysis of biopsy samples was carried out with the help of an electron microscope UEMV-100K.
Results: With the help of transmission electron microscopy, it was found that from the rst minutes after the injection of hemolysate of isogenic erythrocytes into the rats, aggregates of erythrocytes, clumps of blood plasma, clusters of brin monomer masses, bundles of brin bers, platelet and homogeneous were present in the connective tissue of the gums, and in particular in the lumens of hemocapillaries microthrombi, which conrms damage to the ultrastructures of the periodontium, which lead to the development of a pathological process, which is described when simple coagulation dystrophy is reproduced.
Conclusions: Coagulative damage to the ultrastructural elements of the periodontal nervous system is one of the important factors in the pathogenesis of dystrophic periodontal damage. Under these conditions, trophic disturbances occur, similar to those that occur when the integrity of the nerve is disturbed – neurotrophic mechanism of dystrophy.
KEY WORDS: Сoagulation dystrophies, generalized decompensated thrombinogenesis, periodontium, nerves of the gingival mucosa membranes

У споминi висвiтлено основнi вiхи життя та рiзно­плановi  аспекти  дiяльностi  завiдувача  кафедри  xipypriчнoї стоматологii: та щелепно-лицевоi: xipyprii: Львiвського нацiнального медичного унiверситету iменi Данила Галицького (1992-2012 рр.) професора 1. М. Гатя, який зробив значний вне­сок у розвиток xipypriчнoi: стоматологii: в Українi. lван Миросла­вович залишиться у нашiй пам'ятi як свiтла людина з багатим життевим досвiдом та високим професiоналiзмом.