УДК 617.731-007.23-02-036.1-07-08(048.8) 

Хронічна рецидивуюча запальна оптична нейропатія: діагностичні стратегії та лікування (огляд літератури). Негрич Т.І., Копчак М.Б., Кирилюк С.Я. У статті представлено огляд та аналіз наукових праць щодо проблематики хронічної рецидивуючої запальної оптичної нейропатії, критеріїв її діагностики та методів лікування. Хронічна рецидивуюча запальна оптична нейропатія, уперше описана в 2003 році, – це автоімунне запальне захворювання зорового нерва невідомої етіології, що супроводжується частими больовими епізодами оптичного невриту, з чіткою реакцією на стероїдну терапію та рецидивами після її відміни. Проведено аналіз закордонних праць, опублікованих у базах даних E-Library, CrossRef, PubMed, Web of Science, Scopus з метою систематизації даних щодо етіології, патогенезу, клінічних проявів, діагностичних критеріїв, диференційної
діагностики та лікування цього патологічного стану. Установлено, що хронічна рецидивуюча запальна оптична нейропатія є рідкісною, рецидивуючою, кортикостероїдно-залежною зоровою нейропатією, при якій відсутній інший неврологічний дефіцит, не виявляється етіологічний чинник та є діагнозом виключення. Важливість виявлення таких пацієнтів зумовлена тим, що призначення відповідної імуносупресивної терапії спричинює ремісію захворювання.

Ключові слова: хронічна рецидивуюча запальна оптична нейропатія, рецидивуюча ідіопатична оптична
нейропатія, діагностика, лікування, огляд

Abstract. Сhronic relapsing inflammatory optic neuropathy: diagnostic strategies and treatment (literature review). Nehrych T.I., Kopchak M.B., Kyryliuk S.Ya. The article presents a review and analysis of scientific works on the problem of chronic relapsing inflammatory optic neuropathy, its diagnostic criteria and treatment methods. Chronic relapsing inflammatory optic neuropathy, first described in 2003, is an autoimmune inflammatory disease of the
optic nerve of unknown etiology, accompanied by frequent painful episodes of optic neuritis, with a clear response to steroid therapy and relapses after its withdrawal. An analysis of foreign works published in the E-Library, CrossRef, PubMed, Web of Science, Scopus databases was carried out in order to systematize data on the etiology, pathogenesis, clinical manifestations, diagnostic criteria, differential diagnosis and treatment of this pathological condition. It has been established that chronic recurrent inflammatory optic neuropathy is a rare, recurrent, corticosteroid-dependent optic
neuropathy in which there is no other neurological deficit, no etiological factor is identified and it is a diagnosis of exclusion. It is important to identify such patients because the appointment of appropriate immunosuppressive therapy causes remission of the disease. 

Key words: chronic relapsing inflammatory optic neuropathy, relapsing idiopathic optic neuropathy, diagnosis,
treatment, review

Background. Back in 1990, Limansky hypothesized acupuncture points (AP) as polymodal re- ceptors of the ecoceptive sensitivity system. In the process of hypothesis development in 2003 an existence of separate functional system of regulation of electromagnetic balance of organism has been substantiated and a working conception of light therapy has been formulated. Recently, we found that disturbances of the geomagnetic field cause a significant immediate modulating effect on the level of immune parameters in the blood. The data available in the literature give grounds for assumptions about the direct effect of disturbances of the geomagnetic field on immunocytes, and indirectly, through immunotropic neurotransmitters and hormones. Our hypothesis is as follows. Disturbances of the geomagnetic field are perceived by acupuncture points (APs). The information obtained is transmitted to neurons and endocrinocytes, the mediators of which, in turn, affect im- munocytes. The purpose of this study is to test this hypothesis.

Abstract. This article examines the growing interest in acupuncture as a potential treatment on the battlefield, particularly for pain relief and aiding the recovery of soldiers. This trend is part of a broader movement toward the integration of complementary and alternative medicine (CAM) into military healthcare systems. The article highlights how acupuncture’s holistic approach, which differs significantly from traditional Western medicine, makes it particularly effective in managing pain by considering the physical, psychological, and other patient characteristics that contribute to imbalances. Modern research and evidence further support the integration of acupuncture into pain management strategies, especially in military contexts. The article also explores the development and application of Battlefield Acupuncture, a protocol designed for rapid pain relief in combat settings. Additionally, the introduction of innovative approaches, such as finger acupuncture for self-help on the battlefield, offers a practical and low-risk alternative for soldiers in field conditions where access to comprehensive medical care may be limited. The effectiveness, simplicity, and potential for self-treatment make acupuncture a valuable tool in military medicine, particularly in resource- constrained environments.
Keywords: battlefield acupuncture, su jok acupuncture, military medicine.

Abstracts

Background. In previous studies, we have shown that electrokinetic index of buccal epithelium (EKI) correlated with some functional and metabolic parameters. Subsequent studies have shown that сhanges in EKI correlated with changes in some parameters of EEG, HRV, hemodynamics, metabolism, immunity and fecal microbiocenosis. Further research in this direction was continued on a significantly increased contingent of patients and with the involvement of new methods and factors of influence. This message starts the presentation of the obtained results. Material and methods. Under a observations were 44 men (49±15 years) and 30 women (51±13 years) without clinical diagnosis or with chronic pyelonephritis in the phase of remission (23 men). We registered caused by the various therapeutic factors changes in EKI, state of the vegetative and hormonal regulation as well as immunity and metabolism, then calculated relationships between changes. Results. In 49 patients the changes in EKI were in the range of ±2,5%, in 19 people EKI increased by more than 2,5% (M±SD=+4,0±1,6%), while in 9 people decreased by more than 2,5% (-4,2±1,7%). The canonical correlation between changes in EKI, on the one hand, and HRV and immunity parameters, on the other, is moderate: R=0,478; p=0,023. The method of discriminant analysis revealed 10 immune and 6 HRV parameters as well as triglycerides and cholesterol, whose changes are characteristic of multidirectional changes in EKI. Conclusion. Electrokinetic index of buccal epithelium responds to therapeutic factors in different directions, accompanied by characteristic changes in a number of parameters of HRV, immunity and metabolism.

Keywords: Electrokinetic index, HRV, hormones, immunity, metabolism, relationships.

Abstract. Spinal dysraphism (SD) or spina bifida (SB) is a congenital deformity that results from embryonic neural tube closure failure during fetal devel- opment. This evidence-based position paper represents the official position of the European Union through the UEMS PRM Section. This paper aims to evaluate the role of the physical and rehabilitation medicine (prM) physician and prM practice for children and adults with spinal dys- raphism. a systematic literature review and a consensus procedure involved all European countries delegates represented in the uEMs prM sec- tion through a delphi process. the systematic literature review is reported together with thirty-two recommendations resulting from the delphi procedure. The professional role of the PRM physician requires specific expertise in the treatment of patients with SD to plan, lead and monitor the rehabilitation process in an interdisciplinary setting and to participate in the assessment of the needs of these patients in the transitional phase from childhood to adulthood, with particular attention to the activity limitation and participation restriction.

Key words: spinal dysraphism; rehabilitation; physical and rehabilitation medicine; Guideline adherence; consensus.