This article presents the data on the effectiveness of the treatment complex we developed on the activity of bone remodelling markers in the oral fluid during the treatment of generalized periodontitis,depending on the blood group.

There has been an increase in reported TBE cases in Europe since 2015, reaching a peak in some countries in 2020, highlighting the need for better management of TBE risk in Europe. TBE surveillance is currently limited, in part, due to varying diagnostic guidelines, access to testing, and awareness of TBE. Consequently, TBE prevalence is underestimated and vaccination recommendations inadequate. TBE vaccine uptake is unsatisfactory in many TBE-endemic European countries. This review summarizes the findings of a scientific workshop of experts to improve TBE surveillance and vaccine uptake in Europe. Strategies to improve TBE surveillance and vaccine uptake should focus on: aligning diagnostic criteria and testing across Europe; expanding current vaccine recommendations and reducing their complexity; and increasing public education of the potential risks posed by TBEV infection.

Hair loss or alopecia is a common dermatological condition affecting up to 2% of the world population. It is often caused by hereditary factors, such as male or female pattern baldness, but it can also result from various environmental factors, an unbalanced diet, or chronic illness. While hair loss is not life-threatening, it can cause significant anxiety, depression, and other psychological problems, ultimately impacting an individual's quality of life. Various treatments for hair loss, including both synthetic drugs, such as minoxidil and finasteride, or medicinal herbs, have been approved by the Food and Drug Administration. Despite synthetic drugs' effectiveness, they may come with potential side effects. Natural remedies have been proposed as a viable option for treating hair loss because many chronic disorders can cause alopecia. As such, this review focuses on identifying alternative, efficient treatment agents with limited side effects. Specifically, it looks into medicinal plants as potential healing agents for treating hair loss. To gather relevant information for the study, multiple databases were searched, including Scopus, PubMed, and Google Scholar. A comprehensive search was conducted using a range of search terms, such as “hair loss”, “alopecia”, “natural remedies for hair loss”, “herbal treatments for hair loss”, and others to extract relevant scientific articles. Many medicinal plants and natural compounds have shown potential in reducing hair loss, thanks to their anti-inflammatory and antioxidant properties and the ability to improve local metabolism when applied externally. According to existing literature, herbal extracts and formulations derived from plants, such as Urtica dioica, Humulus lupulus, Serenoa repens, Vitis vinifera, Pygeum africanum, Cucurbita pepo, etc., as well as certain individual herbal compounds, micronutrients, bee products, and keratin, may be effective in reducing hair loss directly or indirectly. Research suggests that medicinal plants and a variety of natural compounds hold promise in promoting hair growth and preventing alopecia.

The research substantiates Japanese experience of media literacy and oral communication skills development by digital storytelling (DST); reveals theoretical background and current practical application of DST in higher education of Japan. DST has significant advantages as an individual- and situation-oriented tool of oral communication as well as the instrument of psychological and learning influence on society. It is continuously
implemented into Japanese educational and social practice. Famous universities of Japan initiate and
realize scientific and academic projects, extending communication connections of Japanese
population, improving their skills of critical thinking and argumentation, developing desires and
abilities to communicate freely, fluently, confidently and persuasively.
At present DST shows a positive growing tendency as a teaching and learning tool in higher
education of both Japan and Ukraine. This is primarily linked with the global processes of social
digitalization, computerization of education and urgent transferring to distance learning due to the
COVID-19 pandemic. Evidence-based studies prove the efficacy of DST as the learning and
evaluation instrument of oral communication skills, i. e. in English. Moreover, the technology can
be applied in different specialties, i. e. medical one. The healthcare branch was drastically influenced
by quarantine restrictions, having resulted in fundamental transformations of teaching and learning
approaches, implementation of e-learning and telemedicine. DST has a confirmed positive influence
on public health and medical knowledge development. In higher medical education it can be used
as a new type of virtual patients. DST can improve physician-patient communication skills,
professional qualities, tolerance and empathy. 

Persistent left superior vena cava (PLSVC) is not uncommonvenous return anomaly (0,3-0,5% of the general population). It is usually asymptomatic but can complicate transvenous cardiac interventions, particularly implantations of cardiac pacemakers. An 84-year-old woman was referred tohospitalwith frequent syncopal episodes, dizziness, and fatigue. ECG showed atrial fibrillation with bradycardia (35-40 bpm). The patient was fully investigated and was qualified for permanent single-chamber pacemaker implantation.The patient had an isolated persistent left superior vena cava (PLSVC). Additionally, she had right breast cancer, therefore we performed left axillary access for pacemaker implantation. The pacing lead was inserted via left axillary vein through the PLSVC to the coronary sinus. Afterwards, we looped lead in the right atrium which helped us to put it through the tricuspid valve and implant the lead in apex of right ventricle (RV). All lead measurements (sensing, threshold, impedance, slew rate)at implantation were acceptable. The patient was discharged three days post-implantation without any complications. In a 1-year follow-up we have noticed good lead parameters at interrogation and stable lead position on the X-ray. Certainly, clinicians must be aware of this anomaly and the challenges it presents during pacemaker implantation in affected patients, as well as potential solutions to address these challenges.