The purpose of the study was to generalize our experience of using tuberopterygoid (TPG) implants for prosthetic rehabilitation of patients with partial/ total maxillary/ mandibular adentia under immediate loading protocol. The study describes results of the treatment of 105 patients with total/ partial maxillary/ mandibularadentia, who, during 2012-2019 required dental implantation, which was performed using tuberopterygoid implants in combination with other types of cortico-basal implants, with a follow-up period of 5-2 years. Data was extracted from patient records, panoramic post-op X-rays or from interviews with patients. The employment of TPG implants demonstrates a high implant survival rate (95.7%) within 24-60 months of follow-up period. The high cumulative implant survival rate for TPG implants in immediate loading protocol indicates (within the limitations of this study) the reliability of this treatment approach in patients with partial/ total maxillary/ mandibular adentia, independently on their somatic or local status. 

 It is a well-known fact that teeth extraction induces significant dimensional changes of the alveolar ridge [1, 2, 10]. From the point of view of conventional 2-stage implantation this situation requires grafting of the alveolar sockets before implants placement. Nowadays a variety of materials of different origin are present on the market for appropriate bone substitution (synthetic scaffolds: HA, TCP, Bioglass, coral minerals; Ceramic xenografts: Bio-Oss®, Cerabone®ȎOORJHQLF bone (demineralized, lyophilized); ȎXWRJHQLF ERQH FDQFHOORXV FRUWLFDO etc. The expectations of conventional implantologists from grafting procedure are as following: superior results, higher aesthetics, long term predictability, significantly higher success rate, faster healing etc. [18]. But, being honest, the same results are desirable from the point of view of immediate 1-stage implantation and immediate loading as well... Although the concept of immediate implantation and loading requires no bone substitution, even of fresh extraction sockets, because it relies on natural bone healing under the influence of immedi ate loading, the lack of grafting sometimes leads to inappropriate aesthetic results especially in the aesthetically significant areas as frontal maxilla or mandible. The introduction of platelet-rich fibrin (PRF) and autologous dentin (AD) as a grafting material in maxillofacial surgery and implantology drastically changed the attitude of implantologists to bone substitution and made immediate implantation procedure more predictable [3, 4, 5, 11, 13, 15, 16, 17]. Taking into account that immediate implantation and loading, especially in form of Strategic Implant® approach, is associated with multiple teeth extractions, the use of these extracted teeth in combination with PRF as a grafting material can be a superior technique which provides higher aesthetic and functional results. The aim of this work was to study the effectiveness of AD-PRF composition in immediate implantation and loading in the aesthetically crucial areas.