A high incidence of acne, tendency to a chronic course with the formation of resistance to treatment and frequent development of deep forms determine the important medical and social significance of the problem. Acne is one of the most important problems in modern dermatology, being a common cause for cicatricial skin changes, loss of performance capability and social activity and negatively affects in the psycho-emotional state of patients. The topicality of the disease is due to the high degree of its proliferation, chronic and recurrent course, and resistance to existing therapies. The development of acne is due to the combined effect of endogenous and exogenous factors, including the important role played by the changes of immunological reactivity, justifying the administration of immunotropic techniques and drugs in their comprehensive treatment. Reducing the effectiveness of skin diseases treatment, including that of acne, at present, is associated with developing resistance to drugs, which causes the use of non-drug methods in dermatology nowadays., including low-intensity (with capacity of 1-20 mV) laser therapy, which possesses an anti-inflammatory, antibacterial or bacteriostatic action, stimulates the immune system factors , without causing any side effects or complications.
Objective. Тo increase the effectiveness of treatment of аcne during complex treatment that included combined laser therapy with consideration for indicators of systemic immunity.