Increasing incidence of dermatosis at the background of reduced immunological response to the impact
of exo- and endogenous pathogenic agents dictate the necessity of a more profound research of the
problem. In addition, antibiotic and immunosuppressive therapy led to activation of saprobic and
conventionally pathogenic microflora which is believed to play a prevalent role in the development of
dermatosis and, in particular, psoriasis.
Purpose of the research was to study profile of epidermal microflora on the skin of psoriatic patients and
especially on the affected areas in order to determine its impact on the development and course of
psoriasis. 

The trace element imbalance is reflected in the condition and appearance of hair, which in its
composition have the following essential elements: nitrogen, sulfur, phosphorus, zinc, sodium, calcium,
magnesium and copper. The attention of many researchers is drawn to the hypothesis of the influence of
exogenous and endogenous factors on the functional state of the hair, especially essential and toxic
trace elements that cause dryness and thinning

Psoriasis is one of the most common chronic, non-communicable, immune-mediated skin diseases,
affecting over 125 million people worldwide. The means and dosage forms of topical therapy depend
usually on the clinical course pathological process. In recent years, both in the world and in Ukraine,
narrowband UVB phototherapy of psoriasis, because of its efficiency, safety and availability has become a
technique of choice in the treatment of psoriasis patients with different clinical course. NB UVB therapy
method is self-contained and can be used as monotherapy, but combination of emollient, in our view,
adds treat certain advantages. The aim of our study was to examine and evaluate the effectiveness of this
method phototherapy combination of emollient in the treatment of psoriasis. 

Acne is a multifactorial chronic inflammatory disease with primary damage to the pilosebaceous unit and
the polymorphic clinical manifestations associated with overproduction of sebaceous glands,
pathological desquamation of the sebaceous epithelium of the sebum follicles, activation of saprophytic,
conditionally pathogenic microorganisms, and psychoemotional disorders. This is undoubtedly one of
the most common dermatoses in clinical practice, accounting for 20-25% of dermatology consultations.
Today, especially in wartime, acne vulgaris remains a socially important problem in approximately half of
patients with psychoemotional disorders, mainly of a depressive and anxiety associated nature with a
sharp decrease in the quality of life of patients. 

The science of micronutrients (MN) remains at the stage of amassing factual material. Hair is a reliable and non-invasive source of information about the MN content in the body, for its metabolism is slow and only long-term disturbances in the concentration of nutrients can be reflected in it. The attention of many researchers has been drawn to the hypothesis of the influence of exogenous and endogenous factors on the hair functional status, especially with regard to essential and toxic MN. Today a tendency towards an increase in the number of paediatric patients with hair diseases ranging from excessive hair loss to various clinical forms of alopecia is observed.
Objectives. The study was aimed to identify the MN imbalance, manifested through the condition and appearance of hair, to follow structural changes in hair and to assess the influence of internal organ pathologies.