616-001. 32 - 001. 45 - 007. 286- 06 : 616. 833 - 009. 7] - 085. 2/ . 3 ]
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A longitudinal study of 145 military personnel with neuropathic residual limb pain after combat-related amputation demonstrated clinically significant pain in 60% of patients five months after amputation, with symptomatic neuroma predominating. PTSD was one of the most important contributors to neuropathic postamputation pain. A stable moderate direct correlation was found between pain intensity and PTSD symptoms; combat-related PTSD was associated with a 1.9-fold increase in the probability of neuropathic residual limb pain. Rehabilitation should be based on clinical pain phenotyping and a multidisciplinary therapeutic strategy.