Psoriasis is a skin disease that is accompanied by systemic inflammation and affects about 1 to 5% of the population worldwide.The aim of our research was to determine morphological peculiarities of skin lesions in patients with common psoriasis, investigation of the levels of expression of immunohistochemical markers of vascularization. The results of conducted clinical, morphological and immunohistochemical investigations enable to consider importance of neoangiogenesis processes in pathogenesis of this dermatosis and need in elaboration of therapeutic measures with direct influence on this aspect of pathogenesis.
Найбільш розповсюдженими дерматологічними захворюваннями у хворих на діабет типу 2 є сквамозно-гіперкератотична форма мікозу ступней. Шкірна симптоматика розвивається повільно, починаючи з утворення неболючих змозолілостей та гіперкератозу в ділянках, що зазнавали тиску. Приєднанню грибкової інфекції сприяє порушення кровообігу та травматизація шкіри стоп. Однією з ланок вирішення проблеми є підбір необхідного препарату, який містить компоненти с вираженими кератолітичними та гідратуючими властивостями. Метою дослідження стало вивчення клінічної ефективності бальзаму для ніг від змозолілостей та гіперкератозу з протигриб- ковим ефектом.
Characteristic сhanges in the macroorganism state are reflected in the disorders of microbial landscape of all topographical skin zones. It should be noted that the study of the skin microbial landscape in patients with psoriasis have episodic and unstructured nature. Thus, it is claimed that the findings of the skin microbiocoenosis disorder in patients with psoriasis are characterized by changes in the quantitative and qualitative spectrum of microorganisms, in particular, by the appearance of Staphylococcus haemolyticus in the foci, probable increase in the number of Corynebacterium spp., Micrococcus spp., Staphylococcus hominis, Staphylococcus capitis, Staphylococcus aureus on the background of an oppression or a significant increase in the colonization of Staphylococcus epidermidis. The purpose of our work was to investigate the quantitative composition of microscopic flora and the degree of skin induration of patients with psoriasis, depending on the clinical course (clinical form, stage) and duration of the disease.
Laser therapy is a complex of hardware procedures that involve exposure of the skin to light energy and allows getting rid of a number of skin imperfections. The results of the therapy using the Nordlys device, the principle of operation of which is based on the theory of selective photothermolysis, were analyzed and presented. We observed 118 patients (42 men and 76 women aged 18 to 65 years) with different dermatological problems. The Dermatology Life Quality Index (DLQI) was used to determine the effectiveness of the treatment.
Acne is currently referred to a group of dermatoses that cause somatopsychic resonance due to existing or anticipated aesthetic discomfort. A significant impact of the disease on the quality of life was observed in all examined women with acne, the greatest impact being on daily activities and private life, especially in patients with the disease duration of 1 to 5 years. An increase in the level of anxiety, especially the trait one, was also observed in the group of women with duration of the disease of 1 to 5 years. This substantiates the necessity to find new comprehensive methods of treatment for patients with acne, taking into account the impact of the disease on the anxiety and quality of life of patients.