Today, the use of platelet-rich plasma is increasing in clinical practice in various fields of medicine. The plasma therapy is used by dermatologists, dentists, gynecologists, traumatologists and many other specialists in daily practice. Currently, there is a large number of patients seeking medical help with seborrheic dermatitis. However, the complexity of the pathogenesis of seborrheic dermatitis and its sensitivity to medications require from the dermatologist a differential approach in choosing the local therapy.

Psoriasis is a skin disease that is accompanied by systemic inflammation and affects about 1 to 5% of the population worldwide. The aim of our research was to determine morphological peculiarities of skin lesions in patients with common psoriasis, investigation of the levels of expression of immunohistochemical markers of vascularization.

It has been established that patients with psoriasis, which were under observation, had the skin microbial landscape of the lesions formed mainly of S. aureus, S. epidermidis, S. saprophyticus, Bacillus and Micrococcus genera. The clearest microbial contamination of the lesions has been observed in psoriatic erythroderma, slightly less accentuated skin microbial contamination has been found in patients with the widespread form of dermatitis and the presence of arthropathy, and the least number of microorganisms have been found in patients with common psoriasis without complicated phenomena.

Squamous-hyperkeratotic mycosis of feet is the most prevalent dermatological condition in type 2 diabetes patients. The cutaneous symptoms develop slowly, starting with the formation of painless blistering and hyperkeratosis in areas exposed to pressure. The fungal infection adherence is promoted by poor circulation and traumatisation of the feet skin. The selection of a suitable product containing components with distinct keratolytic and hydrating effects is one part of the problem solution.