Psoriasis affects about 2 % of population. In 30—40 % of occurrences arthropathic psoriasis (AP) is diagnosed and it leads to 11—19 % of disability cases development. The article analyses features of anamnesis, clinical, instrumental and laboratory tests related to arthropathic psoriasis, considers the relationship of probable mechanisms of disease aggravation and progression with the definition of a treatment method influencing the dynamics of a disease course.