Toxic epidermal necrolysis (TEN) is one of the most severe reactions of the body to
the action of various xenobiotics with necrosis of the epidermis, mucous membranes and damage to internal
organs, which is accompanied by profound disorders of hemodynamics and homeostasis, often leading to death.
A wide range of bioregulatory effects of nitric oxide, in particular, participation in the development and course of
allergic inflammation (cytotoxic, immunocomplex reactions), suggest the participation of nitric oxide in the
pathogenesis of TEN
Acne (acne vulgaris) is a chronic relapsing skin condition, which occupies one of the leading places in the structure of dermatopathology, especially in young people of working age; it is a common cause of persistent scarring and negatively affects the psycho-emotional state of patients, their quality of life and performance at work. In the scientific works of domestic and foreign authors, there are indications of the relationship between the development, clinical course and severity of acne with the state of microbiota of the skin.
Objective. To study and evaluate the degree of changes in the microbiocenosis of the skin in patients with acne, depending on their clinical course.
Today, the use of platelet-rich plasma is increasing in clinical practice in various fields of medicine. The plasma therapy is used by dermatologists, dentists, gynecologists, traumatologists and many other specialists in daily practice. Currently, there is a large number of patients seeking medical help with seborrheic dermatitis. However, the complexity of the pathogenesis of seborrheic dermatitis and its sensitivity to medications require from the dermatologist a differential approach in choosing the local therapy.
Psoriasis is a skin disease that is accompanied by systemic inflammation and affects about 1 to 5% of the population worldwide. The aim of our research was to determine morphological peculiarities of skin lesions in patients with common psoriasis, investigation of the levels of expression of immunohistochemical markers of vascularization.
Squamous-hyperkeratotic mycosis of feet is the most prevalent dermatological condition in type 2 diabetes patients. The cutaneous symptoms develop slowly, starting with the formation of painless blistering and hyperkeratosis in areas exposed to pressure. The fungal infection adherence is promoted by poor circulation and traumatisation of the feet skin. The selection of a suitable product containing components with distinct keratolytic and hydrating effects is one part of the problem solution.