Abstract: The importance of evaluating the quality of medicinal products is determined by their impact on public health, therefore there are many analytical methods for controlling the chemical composition and bioequivalence of medicines. Falsification of medicines and determining the composition of generics also remain a serious problem, therefore the search and systematization of modern methods of identifying the quality of medicines and methods of combating illegal medicines are relevant and timely. The purpose of the study is to determine effective methods of assessing the quality of medicines and methods of combating falsified medicines, which would meet the country’s demands in conditions of war and economic crisis. The research used methods of analysis, synthesis, systematization, statistical comparison of groups using Student’s t-test, survey and generalization of results. The obtained results revealed alternative methods of quality control of medicinal products in the conditions of economic and war crisis. We identified the prospect of introducing drug marking and assisting pharmaceutical manufacturers and distributors in drug marking. A low level of awareness of the population regarding the methods of assessing the quality of medicinal products and the algorithm of actions in case of detection of low-quality medicinal products was revealed. Among the doctors, there was also an insufficient level of knowledge regarding the assessment of the quality of medicines, which requires the introduction of training of doctors in this field and educational work among the population.

Keywords: Analytics, Falsification of medicines, Medicinal products, Pharmacy, Quality control, 2-D marking drugs

ABSTRACT
Background: The introduction of modern approaches in dentistry requires a review of existing patient care strategies. The growing prevalence of non-communicable diseases (NCDs) in the structure of overall morbidity demonstrates the importance of considering comorbidities when planning dental interventions and medication support.
Objective: The study aims to systematise modern approaches to optimising the drug treatment of patients with NCDs in dental practice on the example of non-alcoholic fatty liver disease and its complications.
Methods: The research methodology included an analysis of modern scientific literature, statistical data and clinical studies.
Results: The relationship between oral diseases and non-alcoholic fatty liver disease is analysed. The pathophysiological mechanisms of this relationship and modern approaches to pharmacological support of patients are considered. Particular attention is paid to using herbal remedies and nutraceuticals in dental practice, which helps reduce systemic inflammation and the risk of complications.
Conclusion: The data obtained indicate the importance of an interdisciplinary approach in treating such patients.

Keywords:periodontitis, surgical dentistry, therapeutic dentistry, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, herbal remedies, nutraceuticals.

The importance of evaluating the quality of medicinal products is determined by their impact on public health, therefore there are many analytical methods for controlling the chemical composition and bioequivalence of medicines. Falsification of medicines and determining the composition of generics also remain a serious problem, therefore the search and systematization of modern methods of identifying the quality of medicines and methods of combating illegal medicines are relevant and timely. The purpose of the study is to determine effective methods of assessing the quality of medicines and methods of combating falsified medicines, which would meet the country’s demands in conditions of war and economic crisis. The research used methods of analysis, synthesis, systematization, statistical comparison of groups using Student’s t-test, survey and generalization of results. The obtained results revealed alternative methods of quality control of medicinal products in the conditions of economic and war crisis. We identified the prospect of introducing drug marking and assisting pharmaceutical manufacturers and distributors in drug marking. A low level of awareness of the population regarding the methods of assessing the quality of medicinal products and the algorithm of actions in case of detection of low-quality medicinal products was revealed. Among the doctors, there was also an insufficient level of knowledge regarding the assessment of the quality of medicines, which requires the introduction of training of doctors in this field and educational work among the population.

 В даний час більше 10 % населення України хворі на жирову хворобу печінки (ЖХП), третина з яких страждає на неалкогольний стеатогепатит (НАСГ) Враховуючи, що стан гепато-біліарної системи впливає на стан тканин ротової порожнини через метаболічні , дисбіотичні і нейро-гормональні механізми, практично майже у всіх хворих на НАСГ спостерігаються ті чи інші стоматологічні ускладнення. В свою чергу, стоматологічні захворювання можуть впливати на стан гепато-біліарної системи через стоматогенні механізми, пов’язані в значній мірі з тією обставиною, що ротова порожнина є значним мікробним резервуаром (біотопом) в організмі людини, який нараховує більше ніж 500 різних видів бактерій і грибів. Все вищевикладене робить доцільним дослідження патогенетичних механізмів взаємозв’язку ротової порожнини і гепато-біліарної системи і на цій основі розробку ефективних засобів для профілактики та лікування стоматологічних ускладнень,а саме запальних хвороб пародонту у хворих на ЖХП, зокрема, у хворих на НАСГ.