Herpes simplex virus (HSV) can be not only a nosological disease, but also a secondary infection that can affect the severity of the course of other dermatoses. Timely diagnosis and correct therapy of the progression of psoriasis helps related specialists to prevent the occurrence of such diseases. Therefore, the goal of our research is a comprehensive examination of patients with psoriasis, especially with a severe and atypical clinical course of the disease, with the aim of detecting herpes infection and improving the effectiveness of treatment of such patients. The detected changes in indicators of both humoral and cellular immunity in patients with psoriasis are indirect evidence of the negative influence of provoking factors and accompanying pathology on the intensity of the immune response in their body, which in turn leads to the formation of immunodeficiency.

Acne is currently referred to a group of dermatoses that cause somatopsychic resonance due to existing or anticipated aesthetic discomfort. To study the quality of life and the state and trait anxiety indicators in women with acne depending on the duration of the disease.

Laser therapy is a complex of hardware procedures that involve exposure of the skin to light energy and allows getting rid of a number of skin imperfections. The results of the therapy using the Nordlys device, were analyzed and presented. We observed 118 patients (42 men and 76 women aged 18 to 65 years). The Dermatology Life Quality Index (DLQI) was used to determine the effectiveness of the treatment. The Nordlys narrow-spectrum IPL technologies were used to treat couperose and rosacea. The procedures were performed for 5-30 minutes with intervals of 1-2 weeks, 2-5 procedures per course. 17 patients with couperose and 29 patients with rosacea of different stages were treated.

It has been established that patients with psoriasis, which were under observation, had the skin microbial landscape of the lesions formed mainly of S. aureus, S. epidermidis, S. saprophyticus, Bacillus and Micrococcus genera. The clearest microbial contamination of the lesions has been observed in psoriatic erythroderma, slightly less accentuated skin microbial contamination has been found in patients with the widespread form of dermatitis and the presence of arthropathy, and the least number of microorganisms have been found in patients with common psoriasis without complicated phenomena.