Vitiligo and alopecia areata are chronic autoimmune skin diseases in which autoimmune disorders and
psychoemotional stress play a key role in pathogenesis. SARS-CoV-2 infection is associated with systemic
immune dysfunction and a pronounced inflammatory response, which may act as a trigger for the onset
or exacerbation of autoimmune dermatoses. In routine clinical practice, an increasing number of patients
with vitiligo and alopecia areata have been observed following laboratory-confirmed COVID-19,
highlighting the relevance of this study. 

The trace element imbalance is reflected in the condition and appearance of hair, which in its
composition have the following essential elements: nitrogen, sulfur, phosphorus, zinc, sodium, calcium,
magnesium and copper. The attention of many researchers is drawn to the hypothesis of the influence of
exogenous and endogenous factors on the functional state of the hair, especially essential and toxic
trace elements that cause dryness and thinning

The herpes simplex virus (HSV) may be not only a nosological disease but also a secondary infection
which may affect the severity of the course of other dermatoses.
On time diagnostic's and proper therapy of the psoriasis progression help related specialists prevent
occurrence of such diseases. Therefore, the goal of our research is to provide comprehensive
examination of the persons suffering from psoriasis, especially those with the severe or atypical course of
the disease, in order to detect herpetic infection and improve further treatment of these patients. 

The global trend in COVID-19 is that the virus permanently turns into a seasonal disease, such as the flu.
Every year, people will face the problem of the coronavirus, which will continue to mutate. The known
and studied nature of COVID-19 mutations currently does not indicate that the virus has become more
aggressive for the human body. More and more often, COVID-19 proceeds as an acute respiratory viral
infection and evades an immune response. 

Acne is a multifactorial chronic inflammatory disease with primary damage to the pilosebaceous unit and
the polymorphic clinical manifestations associated with overproduction of sebaceous glands,
pathological desquamation of the sebaceous epithelium of the sebum follicles, activation of saprophytic,
conditionally pathogenic microorganisms, and psychoemotional disorders. This is undoubtedly one of
the most common dermatoses in clinical practice, accounting for 20-25% of dermatology consultations.
Today, especially in wartime, acne vulgaris remains a socially important problem in approximately half of
patients with psychoemotional disorders, mainly of a depressive and anxiety associated nature with a
sharp decrease in the quality of life of patients.