UDC [591.4+612.084]:616.716.8 

The research was devoted to the study of the processes of regeneration of the alveolar process of the jaws of experimental animals under the influence of osteotropic drugs. The study was conducted on 50 Wistar rats of herd breeding aged 30 days at the beginning of the experiment. The duration of the experiment was 30 days. The animals were withdrawn from the experiment under thiopental anesthesia, and the jaws were isolated. Excised fragments of jaw bone tissue were fixed in neutral 10 % formalin, decalcified, and embedded in paraffin. The sections were stained with hematoxylin and eosin. The experimental study on animals made it possible to study the effectiveness of the phased application of osteotropic drugs on the processes of local bone resorption. These studies should be taken into account in the development of treatment and prevention complexes for children with osteogenesis disorders.
Key words: rats, experimental research, osteogenesis, complex of preparations, carcinogenic diet.

UDC 616.314-089.5:616.716.4 

The study was dedicated to the improvement of the safety and effectiveness of conduction anesthesia on the mandible using an alternative method of mandibular anesthesia with appropriate anatomical justification and further testing of its clinical effectiveness. The anthropometric parameters of 91 dry anatomical preparations of the adult mandible were studied. Clinical observations were conducted in 440 patients aged 18 to 65 years. A total of 220 anesthetizations were performed using the traditional Inferior Alveolar Block technique and 220 anesthetizations using the Back Low Block technique for the treatment of caries and its complications. According to the results of a comparative evaluation of mandibular anesthesia using the traditional and the proposed methods with the use of standard anesthetic, a greater effectiveness of anesthesia in the Back Low Block technique was proved, as evidenced by an increase in the index of local anesthesia.