Nowadays dermatologist’s arsenal contains numerous pharmacological agents with high efficiency, but achieving the desired results in acne therapy is still not the easiest problem. The aim - to study the modern possibilities of medical and cosmetological correction of acne manifestations based on the analysis of foreign and domestic sources. We conducted a review with further analysis of foreign and domestic sources, domestic, European and American recommendations for the treatment of acne. Publications were searched through the National Center of Biotechnology Information, PubMed, StudMed and GoogleBooks resources.
Today, the use of platelet-rich plasma is increasing in clinical practice in various fields of medicine. The plasma therapy is used by dermatologists, dentists, gynecologists, traumatologists and many other specialists in daily practice. Currently, there is a large number of patients seeking medical help with seborrheic dermatitis. However, the complexity of the pathogenesis of seborrheic dermatitis and its sensitivity to medications require from the dermatologist a differential approach in choosing the local therapy.
Psoriasis is a skin disease that is accompanied by systemic inflammation and affects about 1 to 5% of the population worldwide.The aim of our research was to determine morphological peculiarities of skin lesions in patients with common psoriasis, investigation of the levels of expression of immunohistochemical markers of vascularization. The results of conducted clinical, morphological and immunohistochemical investigations enable to consider importance of neoangiogenesis processes in pathogenesis of this dermatosis and need in elaboration of therapeutic measures with direct influence on this aspect of pathogenesis.
Останніми роками дерматологи все частіше звертають увагу на проблему взаємозв’язку захворювань шкіри із вживанням лікарських препаратів. Під нашим спостереженням перебували 64 хворих із ТАД, які проявлялися багатоформною ексудативною еритемою, синдромом Стівенса—Джонсона та токсичним епідермальним некролізом. Лікувальна тактика хворих на токсико-алергійні дерматози має ґрунтуватись на урахуванні чин- ників, що призводять до розвитку цих станів.
Today, the use of platelet-rich plasma is increasing in clinical practice in various fields of medicine. The plasma therapy is used by dermatologists, dentists, gynecologists, traumatologists and many other specialists in daily practice. Platelet-rich plasma is actively used in dermatology after its clinical effectiveness has been established. The plasma therapy method alone, as well as in combination with other methods of treatment, has shown advantages in certain skin diseases: androgenetic alopecia, alopecia areata, chronic vitiligo, melasma, inflammatory nail disorders, psoriasis, acne, post-acne and seborrheic dermatitis. Platelet-rich plasma can suppress cytokine release and limit inflammation by interacting with macrophages, improving tissue healing and regeneration, promoting the formation of new capillaries and accelerating epithelialization. Plasma platelets also play an important role in the host’s defense mechanism at the wound site by producing signaling proteins that attract macrophages. Blood plasma also has antimicrobial activity against Escherichia coli, Staphilococcus aureus, Candida albicans and Cryptococcus neoformans.