Psoriasis affects about2To of population In 30-40% of occurrences arthropathic
psoriasis (AP) is diagnosed and it leads to 11-19% of disability cases development. The article analyses features of
anamnesis, clinical, instrumental and laboratory tests related to arthropathic psoriasis, considers the relationship of
probable mechanisms of disease aggravation and progression with the definition of a treatment method
influencing the dynamics of a disease course.
The objective of our work was to improve the diagnostics of AP patients taking into account some indicators of
the inrmune-epdocrine system and features of the disease course to specify their role in AP pathogenests and to
develop the system of integrated therapy of patients whose locomotor system is affected due to psoriasis

Tlre possible role of viral persistence as an epigenetic factor in the development of
psoriasis is discussed when a specific antigen (virus, especially type 1,2 (HSV 1,2)) is considered as a trigger factor
for direct or indirect action on immunocompetent cells.
The purposeTo evaluate the peculiarities of blood lyrnphocytes phenotyping in patients with psoriasis and
activated chronic Herpes slmplex virus infection compared to patients with psoriasis, activated chronic Herpes
virus infection, and healthy persons during treatment

Introduction & Objectives: . The most common in dermatological practice are psoriasis and acne, the
pathogenesis of which today is considered from the standpoint of immunopathological diseases. The article
analyses features of anamnesis, clinical, instrumental and laboratory tests related to chronic dermatitis (acne,
psoriasis, arthropathic psoriasis (АР)), considers the relationship of probable mechanisms of disease aggravation
and progression.
Objective. The objective of our work was to improve the diagnostics of common chronic dermatoses (acne,
psoriasis, АР) taking into account some indicators of the immune system and features of the disease course to
specify their role in pathogenesis of these disease. 

The science of micronutrients (MN) remains at the stage of amassing factual material. Hair is a reliable and non-invasive source of information about the MN content in the body, for its metabolism is slow and only long-term disturbances in the concentration of nutrients can be reflected in it. The attention of many researchers has been drawn to the hypothesis of the influence of exogenous and endogenous factors on the hair functional status, especially with regard to essential and toxic MN. Today a tendency towards an increase in the number of paediatric patients with hair diseases ranging from excessive hair loss to various clinical forms of alopecia is observed.
Objectives. The study was aimed to identify the MN imbalance, manifested through the condition and appearance of hair, to follow structural changes in hair and to assess the influence of internal organ pathologies. 

Introduction & Objectives: Androgenetic alopecia (AGA) is a non-scarring progressive miniaturisation of hair follicles that develops in individuals with a hereditary predisposition. The incidence of AGA is about 80% of all hair loss cases in men. Early hair loss in men aggravates the psychological state of patients and often interferes with their socialisation.
The study objective was to investigate the quality of life and anxiety indicators in young males with AGA.