Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are systemic autoimmune diseases that may lead to multiorgan failure due to the destruction of small- and medium-sized blood vessels. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may exacerbate autoimmune diseases and induced vasculitis.

Invitation to take part in "Global", "International", and "Worldwide" conferences seem attractive and prestigious and often with affiliation in Europe, USA, Japan or other well-developed Asia countries. Moreover, the possibility of sharing a stage with a "top speaker" and/or eligibility for reduced registration and accommodation fees and being listed in the abstract book on the "international" level might be a hook not only for young researchers but even for experienced ones. A broad range of submissions, low processing fees, increasing authors' citations, high "local" impact factor, an invitation to write an article for money, "gift-authorship”, suboptimal author guidelines or special offers.

RATIONALE: Precision allergy molecular diagnostics allows assessment of cross-reactivity between pollen and food allergens using multiplex
measurement arrays.
METHODS: Data from 8016 ALEX tests performed in different regions of Ukraine in 2017-2019 were assessed in patients from 1 to 78 years old.Correlation analysis was performed by the Spearman method.
RESULTS: Cross-reactions were mostly seen with Betulaceae pollen groups. Sensitization to Alnus, Betula and Corylus pollen alone expressed cross-reactivity to other pollen types in 55-60 % of cases. 51 % of pateints sensitive to Bet v 2 profilin were sensitized to olive pollen profilin Ole e 2 and of date palm profilin Pho d 2. 51-53 % of patients were sensitized to PR-10 Bet v 1 of Betula pollen and Ara h 8 peanut allergen. 52 to 60 % of patients were sensitized to birch and alder pollen PR-10 allergens and to Mal d 1 of apple from the same group. Cross-reaction between alder and celery PR-10 allergens (Aln g 1 and Api g 1) was 50 %. 50 % of patients reacted to profilins of birch and latex (Bet v 2 and Hev b 8).
CONCLUSIONS: Pollen-targeted allergen-specific immunotherapy may possibly impact pollen-food oral allergy syndromes based upon allergen
cross-reactivit.