UDC: 616.132.11:616.12-005.4]-055.1-073.756.8

Aortic root requires preliminary preoperative analysis for coronary artery bypass graft (CABG) in coronary heart disease (CHD). The dimensions of the aorta correlate with anthropometric indicators. The purpose of the study: to establish the relationship between sinuses of Valsalva height, coronary artery ostia height and biometric parameters (age, height, weight, body surface area and body mass index) in men with CHD using computed tomography. Research materials and methods include contrast-enhanced computed tomography images of the aorta of men with verified CHD. According to growth parameters, division into 2 groups was made. The sinuses of Valsalva height and right and left coronary artery ostia height were measured. Clinical data were analyzed: age, height, body weight, body surface area (BSA) and body mass index (BMI). Statistical analysis: Student's t-test, Kendall's rank correlation method, Pearson's linear correlation, Fisher's multifactorial regression analysis. Analysis of the results of computed tomography of 30 men with CHD (average age 60.80±10.63 years) showed that the average values of the three sinuses of Valsalva height were approximately at the same level. The results of the Pearson linear correlation evaluation showed the absence of a proven relationship between biometric indicators and morphometric data according to CT in men with CHD (p>0.05). Multifactor regression analysis proved the inverse significant influence of weight and the direct significant influence of BMI and BSA on the dependence of left coronary artery ostia height. The multiple correlation coefficient was R=+0.55, with p=0.023, SEE=2.74. Prediction
of the level of left coronary artery ostia height in men with CHD was carried out with confirmation of the constructed model. In the first group of short men (n=11) with CHD (average age 60.11±12.63 years, height 1.677±0.023 m), an inverse correlation between height and left coronary artery ostia height (tb=-0.56, p=0.034). Reliable direct relationships between the left coronary artery ostia height parameter and several anthropometric indicators were established: with weight - a direct strong relationship (tb=+0.72, p=0.007), with BMI - a direct relationship of medium strength (tb=+ 0.67, p=0.008), with BSA - average strength direct connection (tb=+0.58, p=0.023). The relationship between the value of the right coronary artery ostia height and the BSA indicator - the inverse of the average strength correlation (tb=-0.51, p=0.046) was proved. Relationships between morphometric parameters and age were not proven. Thus, in men with CHD, left coronary artery ostia height correlates with weight, BMI, and BSA. In short men with CHD, there is
an inverse relationship between left coronary artery height and height; direct relationships with weight, BMI and BSA.

UDC 611.132:616.132-007.271-055.2]-07

The aortic root is the area subject to interventions in the correction of congenital or acquired heart defects. Aortic stenosis is characterized by a decrease
in the aortic valve area, which impedes blood flow from the left ventricle to the aorta. In aortic stenosis, the processes of degeneration and calcification of
the aortic valve change the geometry of the aortic root. Modern endovascular methods of correcting severe aortic stenosis (for example, transcatheter aortic valve implantation, TAVI) involve detailed morphometric analysis of the aortic root and adjacent structures [1, 2]. Data on the correlation between anthropometric data and mathematical measurements of the aorta at different intervals differ among the authors [3-5]. Obviously, the variability of growth, body weight and body mass index calculated according to them, body surface area differ in different gender and ethnic groups [3, 6, 7]. Data on the morphometry of the height of the aortic sinuses, the branching of the coronary arteries ostia using computed tomography in females with severe aortic
stenosis in Ukraine could not be found in the medical literature.

Severe aortic stenosis still remains a widespread form of valvular heart disease1. Innovative cardiac techniques, such as transcatheter aortic valve replacement (TAVI), require morphometric analysis of the aortic root2,3 annulus, sinus of Valsalva, and ascending aorta.\n\nResults\nThe study population
comprised 80 men and 97 women (age: 82 ± 6 years. Aortic root is a complex and interconnected structure. Some components of the aortic root are posterior (noncoronary) sinuses, as well as the right and left coronary sinuses of Valsalva. Within the norm, the right coronary artery and the left coronary artery arise from the coronary sinuses4. Precise evaluation of the height of the Valsalva sinuses and the coronary ostia is necessary when planning endovascular interventions, predicting and preventing complications5,6. Morphometric analysis of the aortic root allows to estimate the height of the aortic sinuses and the height of the coronary ostia using specific measurements. Computed Tomography (CT) is a gold standard for assessing aortic root7 and conducting appropriate assessments.
The aim of the study is to conduct a morphometric analysis of the height of the Valsalva sinuses in men with severe aortic stenosis and to test predictive
modeling of the height of the Valsalva sinuses based on anthropometric and age differences.

UDC: 611.132.2:616.132.2:616.132.11]-055.2-073.756.8

The most common form of cardiovascular disease in Ukraine is coronary heart disease, which is characterized by damage to the coronary arteries. The height of the aortic sinuses and the height of the coronary arteries are assessed when planning interventional procedures and cardiac surgery. Computed tomography can verify structural changes in the coronary arteries and morphometrically evaluate the components of the aortic sac. The purpose of the study: to measure the height of the coronary arteries orifice; height of the aortic sinuses in women with structural changes of the coronary arteries using computed tomography and assess the interdependence of measurements with anthropometric indicators (age, height, weight, body mass index, body surface area). Computed tomography-angiography of the chest of females with coronary arteries were processed. Statistical analysis: Shapiro-Francia test
(correctness of distribution), Student's t-test (comparison of the height of the coronary arteries and the height of the aortic sinuses); Pearson's linear correlation; Fisher's multifactorial regression analysis. The study found a direct correlation between height and measurability in women with coronary artery disease. The value of the growth rate was directly correlated with the height of the right aortic sinus (r=0.85, p=0.001), with the height of the lower edge of the right coronary artery orifice (r=0.74, p=0.01), the height of the upper edge of the left coronary artery orifice (r=0.67, p=0.03), the height of
the upper edge of the right coronary artery orifice (r=0.67, p=0.03). It is proved that with increasing body surface area, the parameters of the right aortic sinus decrease: the inverse strong correlation r=-0.83, p=0.002. Significant direct relationships have been established between most of the measured components of the aortic root. Multifactor regression analysis showed a proven strong effect of anthropometric data and age on the height of the right aortic sinus: R=0.96, at p=0.009 (according to Fisher). This made it possible to build a model for predicting the height of the right aortic sinus depending
on anthropometric and age parameters. Thus, in women with structural lesions of the coronary arteries, the increase in height correlates with an increase in the height of the right aortic sinus, the height of the coronary arteries orifice. An increase in body surface area correlates with a decrease in the height of the right aortic sinus in women with structural lesions of the coronary arteries.

Situs inversus totalis is a rare condition of visceral transposition in thoracic and abdominal cavities. Computed tomography (CT)-based morphometric analysis of the cardiovascular system prior to the surgery helps to describe vessel topography and size, choose the right surgical insertion site, avoid vessel trauma, and prevent hemorrhage during surgical intervention. We present a case report of situs inversus totalis detected incidentally in a 74-year-old male with the acute abdominal syndrome. Appropriate detailed aorta measurements are used to choose an adequate size of the aortic prosthesis during open surgical repair or endovascular aneurysm repair. An accurate assessment of the vessels on CT scans assists in consideration of the catheter diameter and the most reliable cannulation site. Vessel size correlates with morphological conditions (kinking, stenosis, occlusion), which may be considered a risk of organ malperfusion. The anatomical analysis prior to surgery in different anatomical variations may ensure patient safety and predict complications.