Objective: To study the effectiveness of the biocomplex of surfactants based on rhamnolipids Pseudomonas sp. PS-17 (biocomplex PS) as an emulsifier in emulsions for use in dermatology.
Methods: Technological methods of o/w emulsions manufacturing, ultrasonic dispersion, as well as microscopic studies of manufactured emulsions have been used.
Results: To select the concentration of biocomplex PS as an emulsifier, studies of the emulsifying properties of bio complex PS in comparison with polysorbate 80 have been performed, taking into account the similarity of the hydrophilic-lipophilic balance of these substances. Several compositions of emulsions have been studied in which the biocomplex PS has been used as an independent emulsifier in a concentration from 4 to 10%, as well as in combination with other emulsifiers-lanolin and glycerol monostearate.
Conclusion: The creation of stable o/w emulsions requires the use of high concentrations of biocomplex PS as an emulsifier, more than 10%, which is impractical and economically unreasonable. The use of biocomplex PS as a co-emulsifier with emulsifiers of the second type allows obtaining stable emulsions at a total concentration of complex emulsifier 7-10%.
Keywords: Biocomplex PS, Rhamnolipids, Emulsions, Emulsifiers, Biosurfactants

Abstract

The study of the cognitive aspect of translation opens up new possibilities for understanding and analysing the translation process through the prism of cognitive science. By analysing the cognitive processes that take place in the translator's brain while performing translation, it is possible to reveal various aspects of this complex and multifaceted process. The purpose of this article is to conduct a literature review of cognition-oriented translation studies in order to contribute to the development of the science of translation studies. The method included the analysis of related literature from the scientific databases Scopus and Google Scholar. As a result of this study, advanced theoretical models were put forward and developed to reveal the so-called “black box” of the translator, which is considered a key aspect in understanding the cognitive processes of translation. These theoretical approaches aimed to uncover the internal mechanism and strategies used by the translator when performing translation in order to reveal and analyse how these processes occur in the translator's brain. Conclusions – the research focused on translation processes has great potential, as it uses the latest theoretical models and research methods from related cognitive disciplines such as cognitive psychology, cognitive linguistics, neurophysiology and computational linguistics. The paper attempts to identify challenges in cognitive translation research in order to contribute to a broader understanding of the cognitive aspects of translation and to help address key challenges in this area.

The article is dedicated to commemorating Yakub Karol Parnas, an eminent figure in biochemistry
and a professor in the Department of Physiological (Biological) Chemistry at Lviv Medical University. It
underscores the profound impact of akub Parnas on Ukrainian biochemistry, shedding light on intriguing
facets of his personality during his highly productive two decades at Lviv University. His research significantly contributed to unveiling anaerobic glucose metabolism, later acknowledged as the Embden-MeyerhoffParnas pathway. Professor akub Parnas and his Lviv school conducted pivotal studies on enzymatic transformations associated with anaerobic muscle function and alcoholic fermentation, glycogen phosphorolysis,
revelation of TP synthesis within glycolysis, pioneering use of radioactively labeled phosphorus in biological experiments.
K e y w o r d s: biochemistry, Yakub Parnas, Embden-Meyerhoff-Parnas pathway, Lviv

This review summarizes the scientific knowledge concerning the impact of vitamins, magnesium, and trace elements on various mechanisms contributing to the possible treatment and prevention of COVID-19, including its delayed consequences. A search was conducted in various databases, including PubMed, Scopus, ClinicalTrials.- gov, and Web of Science. Among the main mechanisms involved in the effects of the studied micronutrients, immune-boosting, antioxidant and anti-inflammatory effects were also highlighted. The analyzed clinical trials confirmed that supplementation with higher daily doses of some micronutrients can reduce SARS-CoV-2 viral load and hospitalization time. The potential role of most known vitamins in preventing, treating COVID-19, and rehabilitating patients was considered. The most promising agents for combating COVID-19 and its consequences might be the following vitamins: vitamin D, ascorbic acid, polyunsaturated fatty acids (PUFAs), and some B complex vitamins. Inorganic elements deserving attention include magnesium and trace elements, such as zinc, selenium, copper, and iron. Some associations were found between micronutrient deficiencies and COVID-19 severity in children, adults, and older people. Patients can obtain the aforementioned micronutrients from natural food sources or as supplements/- drugs in various dosage forms. The reviewed micronutrients might be considered adjunctive treatment strategies for COVID-19 patients.

Keywords: COVID-19; ascorbic acid; copper; fat-soluble vitamins; iron; magnesium; micronutrients; selenium; vitamin B complex; zinc..

In the current economic conditions, an active search is conducted for cost-effective and well-balanced feeds and feed mixtures for fish farming. The development of functional feeds using biomass of wild algae is becoming a central focus in the fish feed production. Although these supplements offer a promising path to sustainable and environmentally friendly fish feeding, their impact on the ecosystem requires detailed research. The aim of the study was to determine the acute response of Daphnia magna to the influence of new feed products derived from the  wild algae of the Baltic Sea, phycocyanin on its own, and their binary mixture. The study was conducted using the standard aquatic toxicology method. To establish the  48-hour LC50, the  probit analysis method was used. The results showed that D. magna is more sensitive to the effects of phycocyanin, with the following order of toxicity: phycocyanin > the mixture (1:1) > the biomass of Cladophora sp. The median lethal concentrations at 48 h were 100 mg/l, 920 mg/l, and 1720 mg/l, respectively. The obtained data allows to refer the tested compounds to low-hazard substances according to the Globally Harmonized System (GHS). The observed effects were compared with the effects of the mixture noticed in the toxic units (TU) model. In 48 hours, the mixture of the dry biomass of
Cladophora sp. and phycocyanin at a ratio of 1:1 exhibited synergism. The obtained results will allow choosing the optimal ratio of the raw materials used in fish feeds without inflicting harm to the aquatic ecosystem and loss of their nutritional value.