Summary
Aim:
Improving the quality of diagnosis and treatment orthodontic pathology in patient with temporomandibular joint disorders.

Materials and methods: Analysis – to determine objectives and study plan; clinical-diagnostic methods that include dental and radiological examination (to establish the clinical diagnosis of patients with temporomandibular disorders), electronic axiography (to determine the features of the movements of the articular heads of the mandible), instrumental study the models of jaws in the articulator (to diagnose the state of functional occlusion), statistical (to calculate averages and assess the probability of the results).
Results: After developed and implemented algorithm total dental rehabilitation we have eliminated functional disorders in the masticatory muscles and temporomandibular joints, completely restored the lost function of the masticatory apparatus.
Conclusions: Creation of occlusal relations, which are harmoniously combined with the function of masticatory muscles and temporomandibular joints, allowed to achieve the long period of remission, absence of the complications and recurrences of the disease in the near and long term. These points became the criterions that improved effectiveness of scientifically based individual treatment of mandibular disorders.

Key words: temporomandibular joint disorders (TMDs), malocclusion, individual treatment management

słowa kluczowe: zaburzenia skroniowo-żuchwowe (TMD), wada zgryzu, indywidualizacja terapii

Humic substances are a group of macromolecular compounds that are non-living organisms, but are products of plant transformation, animal and microbial residues in natural conditions. The studies revealed that humic substances extracted from sapropel have a wide range of biological properties: antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, membrane and hepatoprotective. They are capable to increase the activity of metabolic processes in the body and normalize the leukocyte blood formula in leukemia as well. The objective of our work was to determine the presence of photoprotective activity of products with different sapropel extract contents on the model of acute photodynamic skin inflammation in rats. Investigation of anti-inflammatory activity of sapropel extract gel samples was carried out on the model of ultraviolet erythema in rats, which was caused by the irradiator "Promin" ZEMI" with a mercury-quartz lamp of DRT 125-1 type. Complete healing of ultraviolet erythema was observed in the group of animals treated with the sapropel extract gel in concentration of 15% and 10%, respectively on the 6th and 7th days after ultraviolet - irradiation. It should be noted that according to the indices of anti-inflammatory activity and skinfold thickness, the comparison product was significantly weaker to the gels with the sapropel extract. The gel with the sapropel extract in 15% concentration showed the best results. Key words: humic substances, sapropel extract, gel, anti-inflammatory activity, UV- erythema