Abstract. The conducted study aimed for the integration of cloud technologies into the educational process to evaluate their influence on different aspects of the professional competence of future doctors. For this, methods of comparative analysis, questionnaire, expert assessment, observation and statistical analysis were used. Results showed that students of the experimental group demonstrated significant improvement in the professional competence of such components as cognitive, motivational-volitional and organizational performance aspects. This confirms the importance of the skill to effectively use digital technologies in both professional and personal life spheres. The use of cloud technologies such as Google Docs, Pbwiki, Sway, Microsoft Azure, and Microsoft Planner led to significant improvements in students’ results. Still, at the beginning, many teachers doubted these tools, although their attitude changed with time. Thus, reconsideration of educational programs to ensure their compliance with world education standards, in particular through the integration of new technologies, contributing to the development of professional competencies is relevant. The scientific novelty of the research is stipulated by the insufficient number of studies devoted to the use of cloud technologies in training future doctors.

Keywords: artificial intelligence, cloud technologies, digital technologies, network technologies, professional competence.

Abstract:Theaim of the article is to determine the effectiveness of simulation training for the development of critical thinking in medical students. The Starkey’s Critical Thinking Test and specialized observation of the critical thinking of doctors in their professional activities were used to check the levels of the studied parameters. The initial diagnostics showed a predominance of low indicators of the general critical thinking of dental students. The medium and low indicators of the parameter were distributed almost equally in the sample of surgical students. The samples recorded a similar division of persons with low, medium, and high levels of critical thinking in professional activity. The delivered simulation training with interactive scenarios resulted in a slight increase in the general indicators of critical thinking in the experimental group (EG) of dental students. No significant dynamics of results for this parameter were recorded in other samples. Critical thinking in professional situations shows positive changes in all control groups (CG) and EGs as a result of simulation training. Therefore, it can be unequivocally stated that educational simulations are an effective tool for the development of clinical thinking. The implementation of interactive scenarios can provide an additional developmental effect. The obtained data enable making the development of professional competencies in medical students more effective. Further research may focus on studying the influence of simulation training on the critical thinking of medical students in other fields (therapeutic, traumatology, neurology, etc.).

Keywords:Criticalthinking. Interactivescenario. Medicalstudents.Simulationtraining.

   Aim: To investigate in an experiment the dynamic changes in the mandible bone following traumatic injury and subsequent defect replacement with an osteoplastic material - natural collagen.
   Materials and Methods: Experiments were conducted on 45 male rabbits aged 6-7 months, weighing 2.5-3.0 kg. The control group included 20 animals
with a bone tissue defect that healed under a blood clot. The experimental group consisted of 20 rabbits where the bone defect was filled with natural collagen (Col-C). Post-traumatic bone tissue status within the defect area was monitored for 84 days by The assessment of jaw macrostructure, radiographic examination, radiovisiography, examination of bone sections under a microscope, and lectin-histochemical analysis of decalcified bone sections.
   Results: A comprehensive examination of the experimental bone defect in the rabbit mandible, following implantation of natural collagen revealed extensive regenerative processes. These processes were observed at both the macroscopic and microscopic levels, corroborating the findings of radiographic and radiovisiographic analyses. Microscopic evaluation further elucidated the sequential nature of these regenerative changes and provided insights into the composition of the newly formed bone tissue.
   Conclusions: The application of the osteoplastic material (Col-C) demonstrated a high capacity to positively influence the processes of neo-osteosynthesis, followed by remodeling of the damaged bone. This ensures reliable functionality of the entire dentoalveolar system.
   KEY WORDS: rabbits, lower jaw/mandible, dentoalveolar system, bone tissue, regeneration, colagen, , radiographic method, lectin-histochemistry

   Aim: to investigate the factors of bacterial virulence of oral microbiotopes against the background of long-term experimental action of an opioid analgesic.
Materials and Methods:The study was performed on 72 white outbred rats, which were injected “Nalbuphine” with a gradual increase in dose for 12 weeks.
The microbial composition and virulence factors of bacteria in the microbiotopes of the oral cavity were studied.
Results: At the end of the 4th week of opioid exposure, the appearance of hemolytic escherichia was noted. At the end of the 8th week the appearance of
capsular bacteria Klebsiella was registered, as a virulence factor. The production of staphylococcal virulence factors – lecithinase, was noted. At the end of the
12th week of opioid use, the appearance of phycomycete fungi was noted, Gram-negative diplococci, Klebsiella, Hemolytic Escherichia coli and Pseudomonas
aureginosa. These changes indicated the development of dysbiotic changes, as well as the gradual formation of foci of the inflammatory process in the oral cavity.
   Conclusions: In the short-term stages of opioid exposure, changes in biocenoses were manifested in an increase in the contamination of certain types of
microorganisms. In the long-term effects of the opioid, the activation of bacterial elements of the microbiocenosis was revealed, which were characterized by
increased expression of virulence factors. At the later stages of opioid exposure, the predominance of gram-negative microflora and the activation of cytotoxic action against the background of suppressed activity of the body’s protective response were established.
KEY WORDS: experiment, oral cavity, microbiotopes, opioid, rats, microorganisms, virulence factors

UDC 616.314.9–002:616.7]:616 – 071.3–053.4(477.83)

A child's physical development level is one of the indicators of public health, as diseases of adulthood originate in childhood. In Ukraine, when examining primary school children, a third of them have disharmonious physical development due to being underweight, and the rest have a deficit in chest circumference and reduced lung capacity. Among dental diseases, dental caries ranks first. In Ukraine, the prevalence of caries in temporary teeth is particularly high, reaching 100%. The number of children with musculoskeletal disorders is also growing. The aim of the study was to assess the prevalence of caries in temporary teeth in children with musculoskeletal pathology de- pending on the level and harmony of their physical development. For this purpose, 285 children aged 5-6 years (142 boys and 143 girls) who attended specialized groups for children with musculoskeletal disorders in kindergartens in Lviv were examined. The damage to the hard tissues of the teeth was studied by the caries intensity index , and the state of physical development of children was assessed by the main anthropometric indicators – height and body weight. The assessment of children's physical development was analyzed by the 2013 guidelines of the Ministry of Health of Ukraine and the National Academy of Medical Sciences by comparing the actual data of each child with the standards on regression scales separately for girls and boys aged five and six years. It was found that children aged 5-6 years with an average level of physical development in terms of height and harmoniously developed body weight have fewer teeth affected by caries than children with anthropometric indicators that go beyond the stan- dard regression scales.Thus, the highest intensity of dental caries was found in children with lower body weight and higher height.

Key words: physical development, caries of primary teeth, pathology of the musculoskeletal system.